PD184352
PD184352 (CAS: 212631-79-3), with the molecular formula C17H14ClF2IN2O2 and a molecular weight of 478.66 g/mol, is a potent MEK inhibitor. This finely powdered compound is primarily utilised in biochemical research, particularly in cell signalling studies. It serves as a valuable tool for investigating the MAPK/ERK pathway, offering insights into cellular processes and potential therapeutic targets.
- IUPAC
- 2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide,CI-1040
- Synonyms
- CI-1040
MEK Inhibition Research
PD184352 is a selective inhibitor of MEK1 and MEK2, key components of the MAPK/ERK signalling pathway. It is widely used in cell biology research to study the effects of MEK inhibition on cell proliferation, differentiation, and survival.
Cell Signalling Pathway Analysis
Researchers employ PD184352 to dissect the intricate mechanisms of cell signalling. Its application helps to understand the role of the MAPK pathway in various physiological and pathological conditions, including cancer and developmental disorders.
Drug Discovery and Development
As a well-characterised MEK inhibitor, PD184352 serves as a reference compound in early-stage drug discovery efforts targeting the MAPK pathway. It aids in the validation of new therapeutic strategies and the screening of novel drug candidates.
| Molecular weight | 478.66 |
|---|---|
| Empirical formula | C17H14ClF2IN2O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥30 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD184352 used for?
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PD184352 is primarily used in biochemical and cell biology research as a selective inhibitor of MEK1 and MEK2, playing a crucial role in understanding the MAPK/ERK signalling pathway and its implications in cellular processes and disease.
What are the CAS number and formula for PD184352?
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The CAS number for PD184352 is 212631-79-3, and its molecular formula is C17H14ClF2IN2O2.
What grade and purity does Tech Serve Solutions supply for PD184352?
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Tech Serve Solutions supplies PD184352 with a purity of ≥98% (HPLC). This compound is supplied for research purposes and is not intended for human or animal use. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should PD184352 be handled and stored?
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PD184352 is classified as hazardous to the aquatic environment (H400) and requires careful handling to avoid release into the environment (P273). It is typically stored at room temperature. Refer to the Safety Data Sheet for comprehensive handling and safety information.
Is PD184352 a controlled substance?
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The provided data does not indicate that PD184352 is a controlled substance. However, users should always verify local regulations.
How is PD184352 packed, shipped, and exported?
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PD184352 is supplied as a white to tan powder. Shipments adhere to relevant regulations, including UN 3077 classification for environmental hazards. Tech Serve Solutions is experienced in global export.
How can I request a quote or sample for PD184352?
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To request a quote or sample for PD184352, please use the contact form on our website or call our sales department. Our team will be pleased to assist you.
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