4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (CAS: 654-62-6) is a specialised organic compound with the molecular formula C7H8F3N3O4S2. This trifluoromethylated sulfonamide derivative serves as a valuable building block in chemical synthesis and is recognised for its role in cell biology research and as a bioactive small molecule. Its unique structural features make it a subject of interest for developing novel chemical entities.
- IUPAC
- 5-Amino-α,α,α-trifluorotoluene-2,4-disulfonamide
- Synonyms
- C7H8F3N3O4S25-Amino-α,α,α-trifluorotoluene-2,4-disulfonamide

Chemical Synthesis
Utilised as a key intermediate and building block in the synthesis of complex organic molecules. Its functional groups allow for diverse chemical transformations.
Bioactive Small Molecule Research
Investigated for its potential biological activities, serving as a starting point for drug discovery and medicinal chemistry programs.
Cell Biology Studies
Employed in research settings to study cellular processes and mechanisms, particularly where enzyme inhibition or modulation is of interest, such as carbonic anhydrase research.
Organic Building Block
A versatile reagent for organic chemists requiring a source of a trifluoromethylated benzene core with sulfonamide functionalities for further derivatization.
| Molecular weight | 319.28 |
|---|---|
| Empirical formula | C7H8F3N3O4S2 |
| Assay | ≥96% (HPLC) |
| Grade | technical |
| Melting point | 241-246 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Ignition residue | ≤2% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide used for?
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This compound is primarily used as a building block in chemical synthesis, in research related to bioactive small molecules, and in cell biology studies. It is of particular interest in research involving carbonic anhydrases.
What are the CAS number and formula for this compound?
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The CAS number is 654-62-6 and the empirical formula is C7H8F3N3O4S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a technical grade with an assay of ≥96% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the primary safety considerations when handling this chemical?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation.
How is 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide packed and shipped?
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Products are typically packed in suitable containers for safe transport. TSS is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quote or a sample for 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide.
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