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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

CAS 654-62-6C7H8F3N3O4S2Chemical Synthesis

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (CAS: 654-62-6) is a specialised organic compound with the molecular formula C7H8F3N3O4S2. This trifluoromethylated sulfonamide derivative serves as a valuable building block in chemical synthesis and is recognised for its role in cell biology research and as a bioactive small molecule. Its unique structural features make it a subject of interest for developing novel chemical entities.

IUPAC
5-Amino-α,α,α-trifluorotoluene-2,4-disulfonamide
Synonyms
C7H8F3N3O4S25-Amino-α,α,α-trifluorotoluene-2,4-disulfonamide
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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (C7H8F3N3O4S2) — chemical structure, CAS 654-62-6; Chemistry, fine chemical supplied by Tech Serve Solutions
A-AMBioactive Small MoleculesBuilding BlocksCell BiologyChemical SynthesisOrganic Building BlocksSulfonamides/SulfinamidesSulfur Compounds More...
01 /Applications

Chemical Synthesis

Utilised as a key intermediate and building block in the synthesis of complex organic molecules. Its functional groups allow for diverse chemical transformations.

Bioactive Small Molecule Research

Investigated for its potential biological activities, serving as a starting point for drug discovery and medicinal chemistry programs.

Cell Biology Studies

Employed in research settings to study cellular processes and mechanisms, particularly where enzyme inhibition or modulation is of interest, such as carbonic anhydrase research.

Organic Building Block

A versatile reagent for organic chemists requiring a source of a trifluoromethylated benzene core with sulfonamide functionalities for further derivatization.

02 /Properties
Molecular weight319.28
Empirical formulaC7H8F3N3O4S2
Assay≥96% (HPLC)
Gradetechnical
Melting point241-246 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36
Ignition residue≤2%

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
654-62-6
MDL number
MFCD00197629
Beilstein registry
1164542
05 /Additional specifications
Gene Informationhuman ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide used for?

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This compound is primarily used as a building block in chemical synthesis, in research related to bioactive small molecules, and in cell biology studies. It is of particular interest in research involving carbonic anhydrases.

What are the CAS number and formula for this compound?

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The CAS number is 654-62-6 and the empirical formula is C7H8F3N3O4S2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product at a technical grade with an assay of ≥96% (HPLC). We do not represent this product as USP, BP, or EP grade.

What are the primary safety considerations when handling this chemical?

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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation.

How is 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide packed and shipped?

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Products are typically packed in suitable containers for safe transport. TSS is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.

How can I request a quote or sample?

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Please contact our sales team via the website or direct email to request a quote or a sample for 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide.

Need 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide in a specific grade or volume?