PDAM
1-Pyrenyldiazomethane (PDAM), CAS 78377-23-8, with the molecular formula C17H10N2, is a fluorescent diazoalkane. It serves as a valuable HPLC derivatization reagent, particularly for the sensitive detection of carboxylic acids. PDAM offers superior detection limits and enhanced chemical stability compared to alternative reagents like 9-anthryldiazomethane, making it a preferred choice in analytical chemistry.
- IUPAC
- 1-Pyrenyldiazomethane,Pyrene, 1-(diazomethyl)
- Synonyms
- 1-PyrenyldiazomethanePyrene, 1-(diazomethyl)

HPLC Derivatization Reagent
PDAM is utilised as a fluorescent derivatization reagent in High-Performance Liquid Chromatography (HPLC). It reacts with carboxylic acids to form stable derivatives that exhibit strong fluorescence, enabling sensitive detection and quantification.
Carboxylic Acid Analysis
Its primary application involves the improved detection of carboxylic acids. The fluorescence imparted by PDAM allows for lower detection limits and greater accuracy in analytical assays compared to non-fluorescent methods or less stable derivatizing agents.
Analytical Chemistry
In analytical chemistry laboratories, PDAM is employed for its chemical stability and favourable detection parameters, offering a reliable method for analysing complex mixtures containing carboxylic acid functionalities.
| Molecular weight | 242.27 |
|---|---|
| Empirical formula | C17H10N2 |
| Storage temperature | −20°C |
| Application | Fluorescent diazoalkane useful as an HPLC derivatization reagent for carboxylic acid detection with better detection limit parameters and greater chemical stability than the commonly used 9-anthryldiazomethane. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Pyrenyldiazomethane (PDAM) used for?
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1-Pyrenyldiazomethane (PDAM) is primarily used as a fluorescent derivatization reagent in HPLC for the sensitive detection of carboxylic acids, offering improved detection limits and chemical stability.
What is the CAS number and molecular formula for PDAM?
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The CAS number for 1-Pyrenyldiazomethane (PDAM) is 78377-23-8, and its molecular formula is C17H10N2.
What grade and purity does Tech Serve Solutions supply for PDAM?
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Tech Serve Solutions supplies PDAM as a research or technical grade chemical. We do not represent this product as USP, BP, EP or any other pharmacopoeial grade.
What are the safety and handling precautions for PDAM?
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PDAM requires careful handling. Essential personal protective equipment includes eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Its WGK Germany rating is 3, indicating a high hazard.
How is PDAM shipped or exported?
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PDAM is carefully packaged to maintain its integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a quote or sample for PDAM?
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To request a quote or a sample of PDAM, please contact our sales team through the Tech Serve Solutions website or your designated account manager.
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