PET-cGMP
PET-cGMP (CAS 78080-27-0, C18H15N5O7PNa) is a specific sodium salt form of the cyclic nucleotide analogue, β-Phenyl-1,N2-ethenoguanosine 3′,5′-monophosphate. With a molecular weight of 467.30, it primarily functions as a research tool in cell biology, particularly in studies related to cell signaling, neuroscience, and protein kinase G (PKG) activity. Its known solubility in water makes it suitable for various biochemical assays and experimental investigations.
- IUPAC
- β-Phenyl-1,N2-ethenoguanosine 3′,5′-monophosphate sodium salt
Cell Signaling Research
PET-cGMP serves as a valuable probe for investigating cellular signaling pathways. It is particularly useful for studying the role of cyclic nucleotides and their downstream effects in various biological processes.
Neuroscience Studies
In neuroscience, this compound aids in exploring neuronal function and signal transduction mechanisms. Its involvement in pathways relevant to neuronal communication makes it a target for research in this field.
Kinase/Phosphatase Biology
PET-cGMP is employed in research concerning protein kinases and phosphatases. It can be used to understand the regulation and activity of enzymes like Protein Kinase G (PKG) and other serine/threonine kinases.
Biochemical Assays
Its defined solubility and stability allow for its use in a range of in vitro biochemical assays. Researchers utilise it to probe enzyme kinetics, receptor binding, and the efficacy of potential modulators.
| Molecular weight | 467.30 |
|---|---|
| Empirical formula | C18H15N5O7PNa |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: ~10 mmol |
| Storage temperature | −70°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Packaging | pkg of 10 μmol |
|---|---|
| Shipped In | dry ice |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PET-cGMP used for?
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PET-cGMP is used in research for cell biology, cell signaling, neuroscience, and kinase/phosphatase studies, particularly those involving Protein Kinase G (PKG).
What are the CAS number and molecular formula for PET-cGMP?
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The CAS number is 78080-27-0 and the molecular formula is C18H15N5O7PNa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PET-cGMP with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade; it is intended for research purposes.
How should PET-cGMP be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for comprehensive guidance. The WGK rating in Germany is 3.
How is PET-cGMP shipped and stored?
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PET-cGMP is shipped on dry ice and should be stored at −70°C.
How can I request a sample or quote for PET-cGMP?
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To request a sample or a quote, please contact our sales department through the website or by phone.
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