p-Toluenesulfonamide
p-Toluenesulfonamide (CAS 70-55-3) is a chemical compound with the formula CH3C6H4SO2NH2. It functions as a key reagent in organic synthesis, notably participating as a nucleophile in vinyl aziridine opening reactions and as a reagent in the selective aziridination of olefins. Available as a ReagentPlus® grade, it is suitable for various research and synthetic applications.
Nucleophile in Vinyl Aziridine Opening
p-Toluenesulfonamide acts as a nucleophile in tetrabutylammonium fluoride (TBAF) catalyzed vinyl aziridine opening reactions, contributing to the synthesis of complex molecules.
Reagent for Olefin Aziridination
Utilised as a reagent in dirhodium (II) caprolactamate-catalyzed selective aziridination of olefins, facilitating the formation of strained ring systems.
Organic Synthesis Building Block
Serves as a versatile building block in organic synthesis, supporting the creation of diverse chemical structures and functional groups.
| Molecular weight | 171.22 |
|---|---|
| Linear formula | CH3C6H4SO2NH2 |
| Assay | 98% |
| Grade | ReagentPlus® |
| Application | p-Toluenesulfonamide has been employed:• as nucleophile during tetrabutylammonium fluoride (TBAF) catalyzed vinyl aziridine opening reaction1• as reagent during selective aziridination of olefins catalyzed by dirhodium (II) caprolactamate2 |
| Melting point | 134-137 °C(lit.) |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 202 °C / 395.6 °F |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CA1(759), CA2(760), CA5A(763), CA5B(11238) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary uses of p-Toluenesulfonamide?
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p-Toluenesulfonamide is primarily used in organic synthesis as a nucleophile in vinyl aziridine opening reactions and as a reagent for the selective aziridination of olefins. It also serves as a general building block in chemical synthesis.
What is the CAS number and chemical formula for p-Toluenesulfonamide?
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The CAS number for p-Toluenesulfonamide is 70-55-3, and its chemical formula is CH3C6H4SO2NH2.
What grade and purity is p-Toluenesulfonamide typically supplied at?
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p-Toluenesulfonamide is supplied at a purity of 98%, as indicated by its ReagentPlus® grade.
What are the main hazards associated with p-Toluenesulfonamide?
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p-Toluenesulfonamide is classified with the GHS07 symbol and carries a warning signal word. It causes serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used when handling.
How is p-Toluenesulfonamide typically packed, shipped, and exported?
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As a global supplier and exporter, TSS ensures p-Toluenesulfonamide is packed and shipped according to relevant chemical transport regulations to maintain product integrity and safety during transit.
How can I request a quote for p-Toluenesulfonamide?
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To request a quote for p-Toluenesulfonamide, please contact our sales team through the TSS website or via direct inquiry, providing your specific quantity and delivery requirements.
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