Cholesteryl chloroformate
Cholesteryl chloroformate (CAS: 7144-08-3; C28H45ClO2) is a white crystalline solid with a molecular weight of 449.11 g/mol. This compound is recognised for its utility in organic synthesis, particularly as a chiral building block. Its unique thermal properties, exhibiting distinct phase transitions, make it valuable in materials science, especially in the development of liquid crystals and organic electronics. Tech Serve Solutions supplies this reagent for research and development purposes.

Chiral Synthesis
As a derivative of cholesterol, cholesteryl chloroformate serves as a chiral building block in asymmetric synthesis. It can be employed to introduce the bulky, chiral cholesteryl moiety into various organic molecules, enabling the synthesis of complex chiral targets.
Liquid Crystal Research
The compound exhibits thermotropic liquid crystalline behaviour, transitioning between crystalline, cholesteric, and isotropic phases at specific temperatures. This characteristic makes it a subject of interest in materials science for developing novel liquid crystal displays and optical materials.
Organic Electronics
Cholesteryl chloroformate and its derivatives are explored for applications in organic and printed electronics. Its unique molecular structure can influence the electronic and optical properties of organic semiconductor materials.
Chemical Synthesis Intermediate
This reagent functions as a versatile intermediate in the synthesis of more complex organic compounds. Its reactive chloroformate group allows for facile derivatization and incorporation into larger molecular frameworks.
| Molecular weight | 449.11 |
|---|---|
| Empirical formula | C28H45ClO2 |
| Assay | 95%95% |
| Optical activity | [α]27/D −28°, c = 2 in chloroform |
| Melting point | 115-117 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Transition Temp | crystalline phase to cholesteric phase 117.8 °Ccholesteric phase to isotropic phase 125.3 °C |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cholesteryl chloroformate used for?
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Cholesteryl chloroformate is primarily used as a chiral building block in asymmetric synthesis, in research related to liquid crystals and organic electronics, and as a general intermediate in chemical synthesis.
What are the CAS number and chemical formula for Cholesteryl chloroformate?
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The CAS number for Cholesteryl chloroformate is 7144-08-3, and its chemical formula is C28H45ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cholesteryl chloroformate with an assay of 95%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety hazards associated with Cholesteryl chloroformate?
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Cholesteryl chloroformate is classified as Dangerous (GHS05, Signal Word: Danger) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, must be used when handling this substance. It requires careful handling in a well-ventilated area.
How is Cholesteryl chloroformate packed and shipped?
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Cholesteryl chloroformate is packed and shipped according to international regulations for hazardous materials. It is classified as UN 3261, Class 8, Packing Group II, for transportation.
How can I request a sample or a quote for Cholesteryl chloroformate?
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To request a sample or a quote for Cholesteryl chloroformate, please contact our sales team through the website or by phone, providing your specific requirements.
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