p-Toluenesulfonhydrazide
p-Toluenesulfonhydrazide (CAS 1576-35-8), with the linear formula CH3C6H4SO2NHNH2 and a molecular weight of 186.23 g/mol, is a sulfur compound belonging to the sulfonyl hydrazide class. It serves as a versatile building block in organic synthesis. This chemical is commonly employed as a reagent in various chemical transformations, particularly in the preparation of heterocyclic compounds and in functional group modifications. Its applications are primarily within research and industrial chemical synthesis.
- IUPAC
- p-Toluenesulfonic acid hydrazide,p-Toluenesulfonyl hydrazide,Tosylhydrazide
- Synonyms
- p-Toluenesulfonic acid hydrazidep-Toluenesulfonyl hydrazideTosylhydrazide

Organic Synthesis Reagent
p-Toluenesulfonhydrazide is utilised as a key reagent in various organic synthesis pathways. It facilitates the introduction of specific functional groups and is instrumental in the construction of complex organic molecules.
Heterocyclic Compound Synthesis
This compound is frequently employed in the synthesis of diverse heterocyclic ring systems. Its reactivity allows for cyclisation reactions, leading to the formation of pharmacologically relevant scaffolds.
Chemical Intermediate
It functions as a valuable intermediate in multi-step synthesis processes. The tosylhydrazide moiety can be readily transformed into other functional groups, making it a useful precursor for more complex targets.
| Molecular weight | 186.23 |
|---|---|
| Linear formula | CH3C6H4SO2NHNH2 |
| Assay | ≥95% (HPLC) |
| Melting point | 103-108 °C(lit.) |


Hazard statements
- H242Heating may cause a fire
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 3226A3 4.1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Toluenesulfonhydrazide used for?
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p-Toluenesulfonhydrazide is primarily used as a building block and reagent in organic synthesis, particularly for the preparation of heterocyclic compounds and other complex organic molecules.
What is the CAS number and chemical formula for p-Toluenesulfonhydrazide?
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The CAS number for p-Toluenesulfonhydrazide is 1576-35-8, and its linear chemical formula is CH3C6H4SO2NHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Toluenesulfonhydrazide with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should p-Toluenesulfonhydrazide be handled safely?
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p-Toluenesulfonhydrazide is a flammable solid and toxic if swallowed. It requires careful handling with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Store in a cool, well-ventilated area away from heat and ignition sources.
Is p-Toluenesulfonhydrazide packed and exported by TSS?
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Yes, Tech Serve Solutions offers p-Toluenesulfonhydrazide for sale and can facilitate packing and export globally.
How can I request a sample or quote for p-Toluenesulfonhydrazide?
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To request a sample or a quote for p-Toluenesulfonhydrazide, please contact our sales department through the website or by phone.
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