Norphenylephrine hydrochloride
Norphenylephrine hydrochloride (CAS: 4779-94-6), with the molecular formula HOC6H4CH(CH2NH2)OH · HCl and a molecular weight of 189.64 g/mol, is an organic compound within the amino alcohol class. It serves as a valuable building block in chemical synthesis. Its documented application includes its use in scientific studies, such as investigating the physiological effects of related compounds on biological systems like the isolated rabbit heart.
- IUPAC
- α-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride,3,α-Dihydroxyphenethylamine hydrochloride
- Synonyms
- α-(Aminomethyl)-3-hydroxybenzyl alcohol hydrochloride3,α-Dihydroxyphenethylamine hydrochloride

Research Chemical
Norphenylephrine hydrochloride is utilised in laboratory settings for various research purposes. Its properties make it a useful compound for investigating biochemical pathways and pharmacological effects in scientific studies.
Chemical Synthesis Intermediate
As an organic building block, this compound can be employed in the synthesis of more complex molecules. Its functional groups allow for further chemical modification in the development of novel chemical entities.
Pharmacological Studies
Historically, Norphenylephrine hydrochloride has been used in research to study the effects of phenylephrine-like substances. For instance, it was employed in studies involving the isolated heart of rabbits to understand specific physiological responses.
| Molecular weight | 189.64 |
|---|---|
| Linear formula | HOC6H4CH(CH2NH2)OH · HCl |
| Assay | 98% |
| Application | Norphenylephrine hydrochloride was used in the study of the effects of phenylephrine on the isolated heart of rabbit1. |
| Melting point | 162-164 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Norphenylephrine hydrochloride used for?
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Norphenylephrine hydrochloride is primarily used as a research chemical and an intermediate in chemical synthesis. It has also been utilised in studies investigating the effects of phenylephrine on biological systems, such as the isolated rabbit heart.
What are the CAS number and molecular formula for Norphenylephrine hydrochloride?
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The CAS number for Norphenylephrine hydrochloride is 4779-94-6, and its linear formula is HOC6H4CH(CH2NH2)OH · HCl.
What grade and purity does Tech Serve Solutions supply for Norphenylephrine hydrochloride?
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Tech Serve Solutions supplies Norphenylephrine hydrochloride with an assay of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling Norphenylephrine hydrochloride?
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Norphenylephrine hydrochloride is classified with GHS07 pictogram and a 'Warning' signal word. It carries hazard statement H302, indicating it is harmful if swallowed. Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, should be used. It is classified under WGK Germany 3, indicating it is hazardous to water.
How is Norphenylephrine hydrochloride packaged and shipped?
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Norphenylephrine hydrochloride is carefully packaged to ensure stability during transit and is available for export globally. Specific packaging details can be provided upon request.
How can I request a sample or quote for Norphenylephrine hydrochloride?
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To request a sample or a quote for Norphenylephrine hydrochloride, please contact the Tech Serve Solutions sales team via the website or direct inquiry.
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