Nifedipine

CAS 21829-25-4C17H18N2O6Biochemicals & Reagents

Nifedipine (CAS: 21829-25-4), a dihydropyridine derivative with the molecular formula C17H18N2O6 and a molecular weight of 346.33 g/mol, is a yellow crystalline powder. It functions as a calcium channel blocker. Commonly employed in research settings, Nifedipine is a valuable tool for investigating cellular processes and physiological responses related to calcium ion flux and cardiovascular function.

IUPAC: 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester

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Nifedipine (C17H18N2O6) — chemical structure, CAS 21829-25-4; Life Science, fine chemical supplied by Tech Serve Solutions

Application IndexBayerBioactive Small MoleculesBiochemicals and ReagentsCalcium Channel ModulatorsCell BiologyCell Signaling EnzymesEnzymesInhibitorsand Substrates

01 /Applications

Calcium Channel Blocker Research

Nifedipine is widely utilised in pharmacological research to study the role of L-type calcium channels in various physiological processes, including vascular smooth muscle contraction and cardiac electrophysiology. Its selective action makes it a standard tool for understanding calcium signalling pathways.

Cardiovascular Studies

As a potent vasodilator, Nifedipine is frequently used in experimental models to investigate hypertension, angina, and other cardiovascular conditions. Researchers employ it to explore the mechanisms underlying blood pressure regulation and cardiac contractility.

Cell Biology Research

This compound serves as a valuable reagent in cell biology for probing ion channel function and cellular responses to membrane potential changes. It aids in the study of cell signalling cascades influenced by calcium influx.

02 /Properties

Molecular weight	346.33
Empirical formula	C17H18N2O6
Assay	≥98% (HPLC)
Form	powder
Colour	yellow
Solubility	DMSO: solubleethanol: soluble
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	1
Hazard codes (EU)	Xn
Risk statements (R)	22
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

21829-25-4

MDL number

MFCD00057326

PubChem substance

24277855

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Nifedipine used for?

Nifedipine (CAS: 21829-25-4) is primarily used in research to study calcium channel function, cardiovascular physiology, and cell signalling.

What are the CAS number and molecular formula for Nifedipine?

The CAS number for Nifedipine is 21829-25-4, and its molecular formula is C17H18N2O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Nifedipine with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.

How should Nifedipine be handled safely?

Nifedipine is classified as harmful if swallowed (H302) and requires handling with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Work in a well-ventilated area and avoid dust formation.