Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride
Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride (CAS: 4272-74-6), with the molecular formula C14H21ClN2O3S · HCl and a molecular weight of 369.31 g/mol, is a biochemical reagent. It functions as an enzyme inhibitor, specifically noted for its role in organic covalent modification. This compound is typically used in research settings for its ability to interact with and modulate enzyme activity, contributing to biochemical studies.
- IUPAC
- (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride,(3S)-7-Amino-1-chloro-3-tosylamino-2-heptanone hydrochloride,TLCK,Tosyl-L-lysyl-chloromethane hydrochloride
Enzyme Inhibition Studies
This compound serves as a valuable tool in biochemical research for studying enzyme mechanisms and kinetics. Its inhibitory action helps elucidate the function of specific enzymes within biological pathways.
Biochemical Reagent
As a fine chemical, it is employed in various laboratory settings for experimental purposes. Its properties make it suitable for investigating protein interactions and enzymatic processes.
Organic Covalent Modifier
The molecule is utilised in research concerning organic covalent modifications of biological targets. This application is crucial for understanding enzyme structure-activity relationships and developing targeted biochemical probes.
| Molecular weight | 369.31 |
|---|---|
| Empirical formula | C14H21ClN2O3S · HCl |
| Assay | ≥96% (TLC) |
| Solubility | H2O: soluble50 mg/mL |
| Optical activity | [α]20/D −7.8±0.5°, c = 2% in H2O |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Potency | 10-100 μM effective concentration |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride used for?
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Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride (CAS: 4272-74-6) is used as a biochemical reagent and an enzyme inhibitor in research applications, particularly for studying organic covalent modifications.
What are the CAS number and formula for Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride?
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The CAS number is 4272-74-6, and the empirical formula (Hill notation) is C14H21ClN2O3S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride with an assay of ≥96% (TLC). This is a research-grade chemical and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for this product?
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This compound is a Warning product, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride is typically stored at −20°C. We adhere to all international regulations for the safe packing, shipping, and export of fine chemicals.
How can I request a quote or sample?
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To request a quote or a sample of Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride, please contact our sales team through the website or by phone.
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