N-(Hydroxymethyl)nicotinamide
N-(Hydroxymethyl)nicotinamide (CAS 3569-99-1) is a pyridine-based organic compound with the molecular formula C7H8N2O2 and a molar mass of 152.15 g/mol. The N-hydroxymethyl derivative of nicotinamide, it presents as a crystalline solid (melting point 152-154 °C) and serves chiefly as a heterocyclic building block and fine-chemical intermediate in research and chemical synthesis. Tech Serve Solutions supplies it as a high-purity reagent for laboratory and process-development use.
- IUPAC
- 3-Pyridinecarboxylic acid N-hydroxymethylamide
- Synonyms
- N-(Hydroxymethyl)nicotinamide3-Pyridinecarboxylic acid N-hydroxymethylamideN-(Hydroxymethyl)-3-pyridinecarboxamideN-MethylolnicotinamideNicotinamide N-hydroxymethyl derivative
Heterocyclic building block
Used as a functionalised pyridine (nicotinamide) building block in organic and medicinal chemistry, providing both an amide and a reactive hydroxymethyl group for onward derivatisation.
Pharmaceutical and fine-chemical intermediate
Serves as an intermediate in the synthesis of more complex nitrogen-containing molecules and active-ingredient candidates during research and process development.
Chemical synthesis and methodology
Applied in laboratory-scale synthesis where an N-hydroxymethyl amide handle is required, including studies of aminomethylation and related transformations of nicotinamide.
Reference and research reagent
Supplied at 98% assay for use as a research reagent and characterisation standard in analytical and method-development work.
| Molecular weight | 152.15 |
|---|---|
| Empirical formula | C7H8N2O2 |
| Assay | 98% |
| Melting point | 152-154 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(Hydroxymethyl)nicotinamide used for?
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It is used primarily as a heterocyclic building block and fine-chemical intermediate in organic and medicinal chemistry. The pyridine ring with its amide and hydroxymethyl groups makes it useful for the synthesis of more complex nitrogen-containing molecules in research and process-development settings.
What is the CAS number and molecular formula of N-(Hydroxymethyl)nicotinamide?
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The CAS number is 3569-99-1 and the molecular formula is C7H8N2O2, with a molecular weight of 152.15 g/mol. Its MDL number is MFCD00010437 and its EC number is 222-668-4. It is also known as 3-pyridinecarboxylic acid N-hydroxymethylamide.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(Hydroxymethyl)nicotinamide at a typical assay of 98% as a research/technical-grade reagent. We do not represent this material as USP, BP or EP pharmacopoeial grade. A Certificate of Analysis is provided with each batch, and specific assay or specification requirements can be discussed at the time of enquiry.
What are the safety and handling requirements for N-(Hydroxymethyl)nicotinamide?
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It carries GHS pictogram GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection (eyeshields) and an N95-type dust mask, avoid dust formation, and follow precautionary measures P261 and P305+P351+P338. The German Water Hazard Class (WGK) is 3, so prevent release to the environment.
How is N-(Hydroxymethyl)nicotinamide packed, shipped and exported?
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The compound is packed as a solid in sealed, appropriately labelled containers sized to the order, from gram quantities to bulk. Tech Serve Solutions ships internationally with full documentation, including a Certificate of Analysis and Safety Data Sheet, and arranges compliant export logistics on request.
How do I request a sample or a quote?
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Contact Tech Serve Solutions with the quantity, required assay and your destination, and our team will respond with availability, lead time and a quotation. Samples can be arranged for evaluation where appropriate.
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