N-(Benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine
N-(Benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine (CAS 68471-58-9; C13H15NO2; molar mass 217.26 g/mol) is a benzyloxycarbonyl- (Cbz-) protected tetrahydropyridine used as a heterocyclic building block in fine-chemical and pharmaceutical-intermediate synthesis. The Cbz group masks the ring nitrogen while leaving the cyclic enecarbamate available for downstream functionalisation. Tech Serve Solutions supplies it as a research-grade reagent (97% assay) for laboratory and process-development use, with global sourcing and export.
- Synonyms
- N-(Benzyloxycarbonyl)-1,2,3,4-tetrahydropyridineBenzyl 3,4-dihydropyridine-1(2H)-carboxylate1-Cbz-1,2,3,4-tetrahydropyridineN-Cbz-1,2,3,4-tetrahydropyridineCbz-1,2,3,4-tetrahydropyridineCAS 68471-58-9C13H15NO2
Heterocyclic building block
Serves as a piperidine- and tetrahydropyridine-derived scaffold for constructing nitrogen heterocycles. It is used where a Cbz-protected partially saturated pyridine ring is required for further elaboration.
Pharmaceutical intermediate synthesis
Employed in medicinal-chemistry and process routes toward piperidine-containing targets. The protected ring nitrogen allows selective reactions elsewhere in the molecule before deprotection.
Cbz-protected amine chemistry
The benzyloxycarbonyl group provides a robust, well-established nitrogen-protecting strategy that is typically removed by hydrogenolysis, giving the free amine under mild, orthogonal conditions.
Research and discovery chemistry
Supplied as a research-grade reagent for laboratory-scale exploration of new molecules, structure-activity studies and route scouting in chemical synthesis.
| Molecular weight | 217.26 |
|---|---|
| Empirical formula | C13H15NO2 |
| Assay | 97% |
| Density | 1.123 g/mL at 25 °C |
| Refractive index | n20/D 1.552 |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(Benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine used for?
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It is used as a heterocyclic building block and intermediate in fine-chemical and pharmaceutical synthesis. The benzyloxycarbonyl (Cbz) group protects the ring nitrogen, making the compound useful for assembling and functionalising piperidine- and tetrahydropyridine-type structures before deprotection.
What is the CAS number and molecular formula of N-(Benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine?
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The CAS number is 68471-58-9 and the molecular formula is C13H15NO2, with a molecular weight of 217.26 g/mol. Its MDL number is MFCD10566328.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade reagent with a typical assay of 97%. Reported physical data include a refractive index of n20/D 1.552 and a density of 1.123 g/mL at 25 C. It is not represented as USP, BP or EP pharmacopoeia grade; a certificate of analysis can be provided with each batch.
What are the safety and handling requirements?
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The material is classified GHS06 with the signal word Danger and hazard statement H301 (toxic if swallowed). It is a European Class T (toxic) substance. Avoid ingestion and any hand-to-mouth contact, use appropriate personal protective equipment in a well-ventilated area, and IF SWALLOWED immediately call a poison centre or doctor (P301 + P310). Always consult the Safety Data Sheet before use.
How is N-(Benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine packed, shipped and exported?
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It is packed in suitable laboratory and bulk containers with full hazard labelling and documentation. For transport it is classified under UN 2810, Class 6.1, Packing Group III, and is shipped as a regulated toxic substance in line with applicable dangerous-goods rules. Tech Serve Solutions arranges compliant domestic and export despatch with accompanying SDS and certificate of analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and packaging, and destination. We will respond with availability, lead time and documentation, including the SDS and certificate of analysis, and can arrange samples and export shipping.
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