N-Acetylhomopiperazine
N-Acetylhomopiperazine (CAS 61903-11-5) is a seven-membered diazepane building block with the molecular formula C7H14N2O and a molar mass of 142.20 g/mol. It is the mono-acetylated derivative of homopiperazine (1,4-diazepane), supplied at a typical assay of at least 97.0% (GC) as a research-grade reagent. With one ring nitrogen protected as an acetamide and the other left free, it serves as a versatile intermediate in pharmaceutical and fine-chemical synthesis. Tech Serve Solutions supplies and exports it worldwide.
- IUPAC
- 1-Acetylhexahydro-1H-1,4-diazepine
- Synonyms
- N-Acetylhomopiperazine1-Acetylhexahydro-1H-1,4-diazepine1-Acetylhomopiperazine1-(1,4-Diazepan-1-yl)ethanone1-Acetyl-1,4-diazepaneN-Acetyl-1,4-diazepane
Heterocyclic building block
Used as a C4-to-C8 diazepane scaffold in chemical synthesis, providing a homopiperazine ring with one nitrogen pre-protected as an acetyl group. This selectivity supports controlled functionalisation of the remaining free secondary amine.
Pharmaceutical intermediate
Serves as an intermediate in the preparation of biologically active molecules built on the homopiperazine (1,4-diazepane) motif, a ring system widely employed in medicinal-chemistry programmes. Tech Serve Solutions supplies it for research and manufacturing use.
Protected amine handle
The acetyl group acts as a temporary protecting group on one ring nitrogen, allowing the free amine to undergo alkylation, acylation or reductive amination before the acetamide is removed under standard conditions.
Research and discovery chemistry
Suitable as a reagent and reference compound for laboratory-scale exploratory synthesis, structure-activity studies and route-development work involving substituted diazepanes.
| Molecular weight | 142.20 |
|---|---|
| Empirical formula | C7H14N2O |
| Assay | ≥97.0% (GC) |
| Density | 1.077 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.510 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2735PSN1 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Acetylhomopiperazine used for?
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N-Acetylhomopiperazine is used mainly as a heterocyclic building block and intermediate in pharmaceutical and fine-chemical synthesis. It provides a homopiperazine (1,4-diazepane) ring in which one nitrogen is protected as an acetamide, enabling selective chemistry at the remaining free secondary amine.
What is the CAS number and molecular formula of N-Acetylhomopiperazine?
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Its CAS number is 61903-11-5 and its molecular formula is C7H14N2O, with a molecular weight of 142.20 g/mol. The MDL number is MFCD00674492 and the Beilstein registry number is 606764. It is also known as 1-acetylhexahydro-1H-1,4-diazepine.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Acetylhomopiperazine at a typical assay of at least 97.0% by GC as a technical/research-grade reagent. Reported physical data include a density of 1.077 g/mL at 20 °C and a refractive index n20/D of 1.510. We do not represent this material as USP, BP or EP pharmacopoeial grade; a certificate of analysis accompanies each batch.
Is N-Acetylhomopiperazine hazardous, and how should it be handled?
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Yes. It is classified GHS05 with the signal word Danger and the hazard statement H314 (causes severe skin burns and eye damage). Handle it only with suitable gloves, goggles or face shield and respiratory protection, and follow the precautionary measures P280, P305+P351+P338 and P310. Consult the Safety Data Sheet before use.
How is N-Acetylhomopiperazine packed, shipped and exported?
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It is packed in appropriately sealed, labelled containers sized to the order and shipped with full documentation, including a certificate of analysis and Safety Data Sheet. As a Class 8 corrosive material (UN 2735, packing group III, WGK 3 in Germany), it is consigned in accordance with the applicable dangerous-goods transport regulations. Tech Serve Solutions exports worldwide.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and export options. Samples and bulk quantities can be discussed on request.
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