N-Benzyl-2-nitro-1H-imidazole-1-acetamide
N-Benzyl-2-nitro-1H-imidazole-1-acetamide (CAS 22994-85-0; C12H12N4O3; molar mass 260.25 g/mol) is a crystalline 2-nitroimidazole derivative, the same compound widely known as benznidazole. It pairs a nitroimidazole ring with a benzyl acetamide side chain, melting at about 189-192 °C. Tech Serve Solutions supplies it primarily as a heterocyclic building block and reference material for chemical synthesis, pharmaceutical-intermediate research and analytical laboratories worldwide.
- Synonyms
- N-Benzyl-2-nitro-1H-imidazole-1-acetamideBenznidazoleN-Benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide2-(2-Nitro-1H-imidazol-1-yl)-N-benzylacetamideN-Benzyl-2-nitroimidazole-1-acetamide

Heterocyclic building block
Serves as a nitroimidazole scaffold in chemical synthesis, offering a reactive nitro group and an acetamide handle for onward functionalisation and analogue preparation.
Pharmaceutical-intermediate research
This compound corresponds to benznidazole, a documented antiparasitic agent, making it a useful intermediate and reference substance in medicinal-chemistry and drug-development programmes.
Analytical reference material
Used as an identity and purity reference for method development, calibration and quality-control testing in chromatography and spectroscopy laboratories.
Discovery and library synthesis
Applied in research-scale routes and compound libraries where a 2-nitroimidazole acetamide motif is required as a starting point for further derivatisation.
| Molecular weight | 260.25 |
|---|---|
| Empirical formula | C12H12N4O3 |
| Assay | 97% |
| Melting point | 189-192 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Benzyl-2-nitro-1H-imidazole-1-acetamide used for?
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It is used mainly as a heterocyclic building block and reference material in chemical synthesis, pharmaceutical-intermediate research and analytical laboratories. The compound is the same substance known as benznidazole, a documented antiparasitic agent, so it also functions as an intermediate and reference in medicinal-chemistry work. Tech Serve Solutions supplies it for research and manufacturing use, not for clinical or medicinal application.
What is the CAS number and molecular formula of N-Benzyl-2-nitro-1H-imidazole-1-acetamide?
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The CAS number is 22994-85-0 and the molecular formula is C12H12N4O3, with a molecular weight of 260.25 g/mol. The MDL number is MFCD00243089 and the PubChem substance ID is 24866267. Its reported melting point is approximately 189-192 °C.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Benzyl-2-nitro-1H-imidazole-1-acetamide at a typical assay of 97%, as a technical/research-grade material suitable for synthesis, intermediate and laboratory use. We do not represent this product as USP, BP or EP pharmacopoeia grade. A certificate of analysis can be provided with each consignment, and specifications can be reviewed on request.
What are the safety and handling requirements?
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The product carries GHS07 with the signal word Warning and the hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid generating dust, and work with adequate ventilation. Key precautions include P261 and P305+P351+P338. It is classified WGK 3 (German water-hazard class). Always consult the Safety Data Sheet before use.
How is N-Benzyl-2-nitro-1H-imidazole-1-acetamide packed, shipped and exported?
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It is packed as a solid in sealed, labelled containers sized from research quantities to bulk, using packaging appropriate to the order and destination. Tech Serve Solutions ships and exports globally with full documentation, including the certificate of analysis and Safety Data Sheet. Packaging, labelling and transport are arranged to meet applicable regulations for the shipping mode and country.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will confirm availability, lead time and documentation. Samples can be arranged where appropriate, and quotations are issued promptly for both research-scale and bulk requirements.
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