3-Methylpyridine
3-Methylpyridine (CAS: 108-99-6, Formula: C6H7N) is a pyridine derivative with a molecular weight of 93.13 g/mol. Also known as 3-picoline, this heterocyclic organic compound is a versatile building block. It serves as a crucial intermediate in chemical synthesis, particularly for pharmaceuticals and agrochemicals. Its properties lend it to various applications in organic chemistry research and industrial processes.
- IUPAC
- 3-Methylpyridine,3-Picoline
- Synonyms
- 3-Picoline

Pharmaceutical Intermediate
3-Methylpyridine is employed in the synthesis of active pharmaceutical ingredients (APIs). It is a key component in the construction of complex drug molecules, contributing to the development of various therapeutic agents.
Agrochemical Synthesis
This compound is utilized in the production of pesticides and herbicides. Its pyridine ring structure is valuable for creating molecules with specific biological activities targeting agricultural pests.
Chemical Synthesis
As a heterocyclic building block, 3-Methylpyridine is a fundamental reagent in general organic synthesis. It allows chemists to introduce the 3-pyridyl moiety into larger molecules for diverse research and development purposes.
Material Science
It can be used in the development of novel materials and polymers. The nitrogen atom in the pyridine ring can participate in coordination chemistry and influence material properties.
| Molecular weight | 93.13 |
|---|---|
| Empirical formula | C6H7N |
| Assay | 99% |
| Boiling point | 144 °C(lit.) |
| Density | 0.957 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |
| Vapour pressure | 4.4 mmHg (20 °C) |
| Melting point | −19 °C(lit.) |
| Vapour density | 3.2 (vs air) |
| Autoignition temp | ~1000 °F |



Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 37 °C / 98.6 °F |
| Transport (UN / ADR) | UN 2313 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-20/21/22-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methylpyridine primarily used for?
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3-Methylpyridine is primarily used as a chemical intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in broader organic synthesis and material science applications.
What are the CAS number and formula for 3-Methylpyridine?
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The CAS number for 3-Methylpyridine is 108-99-6, and its empirical formula is C6H7N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methylpyridine with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with 3-Methylpyridine?
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3-Methylpyridine is a dangerous substance. It is flammable (H226), harmful if swallowed or inhaled (H302 + H332), and causes severe skin burns and eye damage (H311, H314). Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, is essential.
How is 3-Methylpyridine packed and shipped?
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3-Methylpyridine is shipped as a UN 2313, Hazard Class 3, Packing Group III substance, adhering to strict international shipping regulations for hazardous materials. Packing details can be provided upon request.
How can I request a sample or quote for 3-Methylpyridine?
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To request a sample or obtain a quote for 3-Methylpyridine, please contact our sales team through the website or by phone, providing your specific requirements.
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