N-(4-Hydroxymethyl-pyridin-3-yl)-2,2-dimethyl-propionamide
N-(4-Hydroxymethyl-pyridin-3-yl)-2,2-dimethyl-propionamide (CAS 653584-64-6; molecular formula C11H16N2O2; molar mass 208.26 g/mol) is a heterocyclic pyridine building block for organic and pharmaceutical synthesis. The molecule pairs a 3-aminopyridine protected as its pivalamide (2,2-dimethyl-propionamide) with an adjacent 4-hydroxymethyl group, giving two complementary handles for selective functionalisation. Tech Serve Solutions supplies it as a research-grade fine chemical to laboratories, contract research organisations and process-development groups worldwide.
- Synonyms
- N-(4-Hydroxymethyl-pyridin-3-yl)-2,2-dimethyl-propionamideN-[4-(hydroxymethyl)pyridin-3-yl]-2,2-dimethylpropanamideN-(4-(hydroxymethyl)pyridin-3-yl)pivalamide2,2-dimethyl-N-[4-(hydroxymethyl)pyridin-3-yl]propanamideCAS 653584-64-6
Pyridine building block for synthesis
Serves as a substituted-pyridine scaffold in multi-step organic synthesis, where the pyridine ring is elaborated into more complex heterocyclic structures.
Pivalamide-protected aminopyridine intermediate
The 2,2-dimethyl-propionamide (pivaloyl) group masks the 3-amino position, allowing directed metalation and selective chemistry elsewhere on the ring before the amine is revealed by deprotection.
Hydroxymethyl functional handle
The 4-hydroxymethyl group offers a primary alcohol for onward transformation, such as oxidation, etherification, esterification or conversion to a leaving group for further coupling.
Pharmaceutical and agrochemical discovery
As a difunctional heterocyclic building block, it supports medicinal-chemistry and agrochemical research programmes that require functionalised aminopyridine cores. Specific end-uses should be confirmed by the customer for their application.
Reference and laboratory use
Suitable as a research reagent and reference material for method development, analytical work and small-scale exploratory chemistry.
| Molecular weight | 208.26 |
|---|---|
| Empirical formula | C11H16N2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-Hydroxymethyl-pyridin-3-yl)-2,2-dimethyl-propionamide used for?
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It is used as a heterocyclic building block in organic and pharmaceutical synthesis. The pivalamide-protected 3-aminopyridine and the adjacent 4-hydroxymethyl group provide two reactive handles for selective functionalisation, making it useful for constructing more complex pyridine-based molecules in research and process-development settings.
What is the CAS number and molecular formula of N-(4-Hydroxymethyl-pyridin-3-yl)-2,2-dimethyl-propionamide?
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Its CAS number is 653584-64-6 and its molecular formula is C11H16N2O2, corresponding to a molar mass of 208.26 g/mol. It belongs to the pyridine class of heterocyclic building blocks.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research/technical-grade fine chemical. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification and Certificate of Analysis, including the assay for the batch offered, are provided on request so you can confirm suitability before purchase.
How should N-(4-Hydroxymethyl-pyridin-3-yl)-2,2-dimethyl-propionamide be handled and stored?
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Handle it as a laboratory research chemical using good chemical-handling practice: wear suitable gloves, eye protection and a lab coat, work with adequate ventilation, and avoid dust, contact and ingestion. Store in a tightly closed container in a cool, dry, well-ventilated place. Always consult the Safety Data Sheet supplied with the consignment for batch-specific hazard, handling and disposal guidance.
How is N-(4-Hydroxymethyl-pyridin-3-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in clean, well-sealed, appropriately labelled containers sized to the order, from gram quantities for research to larger laboratory pack sizes. Tech Serve Solutions exports worldwide with full documentation, including the Certificate of Analysis and Safety Data Sheet, and arranges packaging and transport in line with the applicable shipping regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 653584-64-6, your required quantity and destination, and we will provide pricing, lead time, current specifications and a Certificate of Analysis. Samples can be arranged where available to support your evaluation.
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