N-(4-Formyl-pyridin-3-yl)-2,2-dimethyl-propionamide
N-(4-Formyl-pyridin-3-yl)-2,2-dimethyl-propionamide (CAS 127446-35-9; molecular formula C11H14N2O2; molar mass 206.24 g/mol) is a heterocyclic building block combining a pyridine ring, an aldehyde group and a pivaloyl-protected amine. Supplied as a research-grade fine chemical, it serves chemical synthesis programmes where the reactive formyl handle and directed metalation chemistry support the construction of substituted pyridines and pharmaceutical intermediates. Tech Serve Solutions supplies and exports this compound to laboratory and discovery customers worldwide.
- Synonyms
- N-(4-Formyl-pyridin-3-yl)-2,2-dimethyl-propionamideN-(4-Formylpyridin-3-yl)pivalamideN-(4-formyl-3-pyridyl)-2,2-dimethylpropanamide2,2-Dimethyl-N-(4-formylpyridin-3-yl)propanamideN-(4-formyl-3-pyridinyl)-2,2-dimethylpropanamideCAS 127446-35-9
Heterocyclic building block
Used as a functionalised pyridine scaffold in multistep organic synthesis. The combination of an aromatic aldehyde and a protected amino group on adjacent ring positions enables selective onward transformation.
Pharmaceutical and discovery intermediate
Serves as an intermediate in medicinal chemistry and discovery programmes that build substituted pyridine cores. It is offered for research and manufacturing use, not for clinical or therapeutic application.
Aldehyde-directed transformations
The free formyl group provides a reactive handle for reductive amination, condensation, olefination and related carbonyl chemistry, allowing rapid elaboration of the pyridine framework.
Directed ortho-metalation chemistry
The 2,2-dimethylpropionamide (pivaloylamino) group is a well-established directing and protecting group, supporting regioselective functionalisation of the pyridine ring during synthesis.
Reference and method development
Suitable as a characterised reference material for analytical method development, structure-activity studies and route-scouting in laboratory settings.
| Molecular weight | 206.24 |
|---|---|
| Empirical formula | C11H14N2O2 |
Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-Formyl-pyridin-3-yl)-2,2-dimethyl-propionamide used for?
+
It is used as a heterocyclic building block and synthetic intermediate. Its reactive aldehyde group and pivaloyl-protected amine on a pyridine ring make it useful for constructing substituted pyridines and pharmaceutical intermediates in research and manufacturing settings.
What is the CAS number and molecular formula of N-(4-Formyl-pyridin-3-yl)-2,2-dimethyl-propionamide?
+
The CAS number is 127446-35-9. The molecular formula is C11H14N2O2, with a molecular weight of 206.24 g/mol.
What grade and purity does Tech Serve Solutions supply?
+
It is supplied as a research-grade fine chemical and building block for synthesis. We do not represent it as USP, BP or EP pharmacopoeial grade. Batch-specific assay and certificate of analysis details are confirmed at the time of enquiry; please state your required specification when requesting a quote.
What are the safety and handling precautions?
+
It is classified under GHS07 with the signal word Warning. The hazard statements are H317 (may cause an allergic skin reaction) and H319 (causes serious eye irritation). Wear protective gloves and eye protection (P280). If in eyes, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do (P305 + P351 + P338). Consult the Safety Data Sheet before use.
How is N-(4-Formyl-pyridin-3-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
+
It is packed in appropriately sealed, labelled laboratory and bulk containers sized to your order, with full documentation including a certificate of analysis and Safety Data Sheet. Tech Serve Solutions exports worldwide in line with applicable transport and customs regulations.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with the product name, CAS number 127446-35-9, the quantity and your required specification. We will confirm availability, packaging, lead time and export documentation for your destination.
▶ Related products
4-Amino-2-chloropyridine
C5H5ClN2
Heterocyclic Building Blocks
4-Ethynyl-1-methyl-1H-pyrazole
C6H6N2
Heterocyclic Building Blocks
4-Hydroxyquinoline-3-carboxylic acid ethyl ester
C12H11NO3
Heterocyclic Building Blocks
4-isocyanatopyridine
C6H4N2O
Heterocyclic Building Blocks
5-Chloro-2,8-dimethylquinoline
Heterocyclic Building Blocks
5-Chloro-2-methylene-1,3,3-trimethylindoline
Heterocyclic Building Blocks
5-Chloro-2-thiophenecarbonitrile
Heterocyclic Building Blocks
5-ethynyl-1H-pyrazole
C5H4N2
Heterocyclic Building Blocks▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis