Methyl phenylsulfonylacetate
Methyl phenylsulfonylacetate (CAS: 34097-60-4) is an organic compound with the molecular formula C6H5SO2CH2COOCH3 and a molecular weight of 214.24 g/mol. This sulfone derivative serves as a valuable building block in organic synthesis. It has been employed in the creation of complex natural products and in reactions such as dehydrative alkylation of alcohols, highlighting its utility in chemical synthesis and research applications.
- IUPAC
- Methyl benzenesulfonylacetate
Synthesis of Natural Products
Methyl phenylsulfonylacetate has been a key intermediate in the synthesis of complex molecules, including its documented use in the preparation of (−)-hybridalactone, a marine eicosanoid.
Dehydrative Alkylation Reactions
This compound is utilised in modified Mitsunobu conditions for the dehydrative alkylation of alcohols, followed by a desulfonylation step using magnesium.
Preparation of Indene Derivatives
It has been incorporated into a three-step synthetic route for the preparation of 2-(hydroxymethyl)indene, showcasing its role in building specific molecular architectures.
| Molecular weight | 214.24 |
|---|---|
| Linear formula | C6H5SO2CH2COOCH3 |
| Assay | 97% |
| Boiling point | 165 °C/0.05 mmHg(lit.) |
| Density | 1.305 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.535(lit.) |
| Application | Methyl phenylsulfonylacetate has been used:• in a key step during the synthesis of (−)-hybridalactone, marine eicosanoid isolated from the red alga Laurencia hybrida1• in dehydrative alkylation of alcohols under modified Mitsunobu conditions followed by desulfonylation using magnesium2• in three step synthesis of 2-(hydroxymethyl)indene3 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... LOC129293(129293) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl phenylsulfonylacetate used for?
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Methyl phenylsulfonylacetate is used as a building block in organic synthesis, including the preparation of natural products, in dehydrative alkylation reactions, and for synthesising indene derivatives.
What is the CAS number and molecular formula for Methyl phenylsulfonylacetate?
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The CAS number for Methyl phenylsulfonylacetate is 34097-60-4 and its linear formula is C6H5SO2CH2COOCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl phenylsulfonylacetate with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling recommendations for Methyl phenylsulfonylacetate?
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Handling Methyl phenylsulfonylacetate requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (half-mask respirator). It has a flash point of 78°C (172.4°F), indicating flammability concerns.
How is Methyl phenylsulfonylacetate packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports fine chemicals globally, adhering to all relevant regulations to ensure safe and timely delivery.
How can I request a sample or quote for Methyl phenylsulfonylacetate?
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To request a sample or obtain a quote for Methyl phenylsulfonylacetate, please contact our sales department through the website or by phone.
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