Tetrabutylammonium fluoride hydrate
Tetrabutylammonium fluoride hydrate (CAS 22206-57-1), with the linear formula [CH3(CH2)3]4NF·xH2O and a molecular weight of 261.46 (anhydrous basis), is a vital reagent in organic synthesis. It is particularly recognised for its role in preparing terminal olefins from primary alkyl iodides. This compound serves as a crucial building block in various chemical transformations, offered by TSS with an assay of 98%.
- IUPAC
- TBAF
![Tetrabutylammonium fluoride hydrate ([CH3(CH2)3]4NF·xH2O) — chemical structure, CAS 22206-57-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F22206-57-1.png&w=3840&q=75)
Olefin Synthesis
Tetrabutylammonium fluoride hydrate serves as an effective reagent for the preparation of terminal olefins. It is specifically employed in reactions with primary alkyl iodides to yield the desired olefin products.
Fluoride Source
As a soluble source of fluoride ions, this compound can be utilised in various synthetic applications where a fluoride nucleophile is required. Its tetrabutylammonium counterion enhances solubility in organic solvents.
Deprotecting Agent
In certain organic synthesis pathways, tetrabutylammonium fluoride can act as a deprotecting agent, cleaving specific protecting groups under mild conditions.
| Molecular weight | 261.46 (anhydrous basis) |
|---|---|
| Linear formula | [CH3(CH2)3]4NF·xH2O |
| Assay | 98% |
| Application | Reagent used to prepare terminal olefins from primary alkyl iodides.5 |
| Melting point | 62-63 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrabutylammonium fluoride hydrate used for?
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Tetrabutylammonium fluoride hydrate is primarily used as a reagent in organic synthesis, notably for the preparation of terminal olefins from primary alkyl iodides. It also functions as a soluble fluoride source and a deprotecting agent in specific synthetic contexts.
What are the CAS number and formula for Tetrabutylammonium fluoride hydrate?
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The CAS number for Tetrabutylammonium fluoride hydrate is 22206-57-1, and its linear formula is [CH3(CH2)3]4NF·xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrabutylammonium fluoride hydrate with a purity of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should Tetrabutylammonium fluoride hydrate be handled safely?
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Tetrabutylammonium fluoride hydrate is a corrosive substance (H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, and chemically resistant gloves, must be worn. Handle in a well-ventilated area or with a suitable respirator. Refer to the Safety Data Sheet for detailed handling instructions.
Is Tetrabutylammonium fluoride hydrate a controlled substance?
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Based on the provided data, Tetrabutylammonium fluoride hydrate is not indicated as a controlled substance. However, users should always verify local regulations.
How is Tetrabutylammonium fluoride hydrate shipped and exported?
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Tetrabutylammonium fluoride hydrate is classified under UN 3261, Hazard Class 8, Packing Group II, indicating it is a corrosive solid, acid, or base, n.o.s. TSS handles all shipments in compliance with relevant dangerous goods regulations for export.
How can I request a quote or sample?
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To request a quote or a sample of Tetrabutylammonium fluoride hydrate, please contact our sales team via the website or direct inquiry channels, providing your specific requirements.
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