Methyl phenyl sulfoxide
Methyl phenyl sulfoxide (CAS: 1193-82-4), a key organic sulfur compound with the molecular formula C7H8SO, plays a vital role as a building block in sophisticated chemical synthesis. With a molecular weight of 140.20 g/mol and a purity of ≥97.0% (GC), this sulfoxide is instrumental in the creation of complex molecules. Its applications range from the synthesis of isotopically labelled compounds to its use in the development of potent pharmaceutical agents like nelfinavir.
Synthesis of Labeled Synthons
Methyl phenyl sulfoxide serves as a precursor in the synthesis of isotopically labelled 1,3-dithiane. This labelled synthon is valuable for precise molecular studies and complex organic synthesis pathways.
Pharmaceutical Intermediate
This compound has been employed in the synthesis of nelfinavir, a potent HIV-protease inhibitor. This highlights its significance in the development of critical antiviral medications.
Precursor for Sulfoximines
Methyl phenyl sulfoxide is utilised in the synthesis of sulfoximines, a class of compounds with growing importance in medicinal chemistry and materials science.
Solvent-Water Partitioning Studies
The compound finds application in research studies investigating solvent-water partitioning behaviour. This helps in understanding the lipophilicity and environmental fate of chemical substances.
| Molecular weight | 140.20 |
|---|---|
| Linear formula | CH3SOC6H5 |
| Assay | ≥97.0% (GC) |
| Boiling point | 139-140 °C/14 mmHg(lit.) |
| Refractive index | n20/D 1.5775(lit.) |
| Storage temperature | 2-8°C |
| Application | Methyl phenyl sulfoxide has been used in the synthesis of:• isotopically labelled 1, 3-dithiane, a useful labeled synthon1• nelfinavir, potent HIV-protease inhibitor2• sulfoximines3 and in studies on solvent-water partitioning4 |
| Melting point | 26-29 °C(lit.)26-29 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl phenyl sulfoxide used for?
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Methyl phenyl sulfoxide is used as a building block in chemical synthesis, including the preparation of isotopically labelled 1,3-dithiane, the HIV-protease inhibitor nelfinavir, sulfoximines, and in studies on solvent-water partitioning.
What are the CAS number and formula for Methyl phenyl sulfoxide?
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The CAS number for Methyl phenyl sulfoxide is 1193-82-4, and its linear formula is C7H8SO (CH3SOC6H5).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl phenyl sulfoxide with an assay of ≥97.0% (GC). This product is supplied for laboratory and industrial use; TSS does not represent it as USP, BP, EP or other pharmacopoeial grades unless explicitly stated.
How should Methyl phenyl sulfoxide be handled and stored?
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Methyl phenyl sulfoxide causes skin irritation, serious eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including dust mask type N95 (US), eyeshields, and gloves. Store in a well-ventilated place. Recommended storage temperature is 2-8°C.
Is Methyl phenyl sulfoxide a controlled substance?
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Based on the provided data, Methyl phenyl sulfoxide is not indicated as a controlled substance.
How can I request a sample or quote for Methyl phenyl sulfoxide?
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Please contact our sales team via the website or by phone to request a sample or a formal quotation for Methyl phenyl sulfoxide. We export globally and can assist with your specific requirements.
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