Methyl 3-amino-2-pyrazinecarboxylate
Methyl 3-amino-2-pyrazinecarboxylate (CAS: 16298-03-6, C6H7N3O2) is a heterocyclic organic compound with a molecular weight of 153.14 g/mol. This pyrazine derivative serves as a valuable building block in chemical synthesis. Its primary applications involve the preparation of more complex molecules, notably pteridin-4-ones and various triazolopyrazines, through reactions with diverse chemical reagents.

Synthesis of Pteridine Derivatives
Methyl 3-amino-2-pyrazinecarboxylate is utilized in the synthesis of 2-arylpteridin-4-ones and pteridinediones. These reactions often involve condensation with reagents like aroyl chlorides.
Preparation of Triazolopyrazines
This compound serves as a precursor for piperazine-derived 2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazines. It can also react with isocyanates to form complex heterocyclic structures.
Heterocyclic Building Block
As a functionalised pyrazine, it is a key intermediate in the construction of novel heterocyclic frameworks for research and development in medicinal chemistry and materials science.
| Molecular weight | 153.14 |
|---|---|
| Empirical formula | C6H7N3O2 |
| Assay | 97% |
| Application | Methyl 3-amino-2-pyrazinecarboxylate has been used in: • synthesis of 2-arylpteridin-4-ones1 and piperazine-derived 2-furan-2-yl-[1,2,4]triazolo[1,5-a] pyrazines2• reactions with isocyanates3 and aroyl chlorides1 for conversion to pteridinediones |
| Melting point | 169-172 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3-amino-2-pyrazinecarboxylate used for?
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Methyl 3-amino-2-pyrazinecarboxylate is used as a building block in chemical synthesis, particularly for the preparation of pteridine derivatives and triazolopyrazines.
What is the CAS number and formula for Methyl 3-amino-2-pyrazinecarboxylate?
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The CAS number is 16298-03-6 and the empirical formula is C6H7N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3-amino-2-pyrazinecarboxylate with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety precautions for handling Methyl 3-amino-2-pyrazinecarboxylate?
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When handling Methyl 3-amino-2-pyrazinecarboxylate, it is essential to wear eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) should be used. The compound is classified under WGK Germany 3, indicating a hazard to water.
Is Methyl 3-amino-2-pyrazinecarboxylate a controlled substance?
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The provided data does not indicate that Methyl 3-amino-2-pyrazinecarboxylate is a controlled substance.
How is Methyl 3-amino-2-pyrazinecarboxylate packed, shipped, and exported?
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Tech Serve Solutions can accommodate various packing requirements for domestic and international shipments. Please contact us for specific details regarding export capabilities and shipping for this chemical.
How can I request a sample or quote for Methyl 3-amino-2-pyrazinecarboxylate?
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To request a sample or obtain a quote for Methyl 3-amino-2-pyrazinecarboxylate, please use the contact form on our website or call our sales department directly.
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