Methyl 3-amino-2-thiophenecarboxylate
Methyl 3-amino-2-thiophenecarboxylate (CAS: 22288-78-4, C6H7NO2S) is a heterocyclic organic compound with a molecular weight of 157.19 g/mol. This thiophene derivative serves as a valuable building block in organic synthesis. Its primary applications include the preparation of various heterocyclic compounds, such as thienopyrimidinone analogues, and its utility in the synthesis of complex molecules like quinazolinocarboline alkaloids.
Synthesis of Thienyl Ureas
Methyl 3-amino-2-thiophenecarboxylate has been employed in the synthesis of 4-nitro and 4-aminothienyl ureas, showcasing its utility in creating specific functionalized urea derivatives.
Preparation of Thienopyrimidinone Analogues
This compound is utilised in the preparation of thienopyrimidinone analogues, a class of heterocyclic compounds with potential pharmaceutical relevance.
Total Synthesis of Alkaloids
It played a role in the total synthesis of quinazolinocarboline alkaloids, demonstrating its importance in constructing complex natural product structures.
| Molecular weight | 157.19 |
|---|---|
| Empirical formula | C6H7NO2S |
| Assay | 99% |
| Boiling point | 100-102 °C/0.1 mmHg(lit.) |
| Application | Methyl 3-amino-2-thiophenecarboxylate was used in:• the synthesis of 4-nitro and 4-aminothienyl ureas1• total synthesis of quinazolinocarboline alkaloids2• preparation of thienopyrimidinone analogs3 |
| Melting point | 62-64 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3-amino-2-thiophenecarboxylate used for?
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Methyl 3-amino-2-thiophenecarboxylate is used as a building block in organic synthesis, particularly for preparing thienyl ureas, thienopyrimidinone analogues, and in the total synthesis of quinazolinocarboline alkaloids.
What are the CAS number and formula for Methyl 3-amino-2-thiophenecarboxylate?
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The CAS number is 22288-78-4, and the empirical formula is C6H7NO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3-amino-2-thiophenecarboxylate with a minimum assay of 99%. This is a research-grade chemical and not represented as USP, BP, or EP.
How should Methyl 3-amino-2-thiophenecarboxylate be handled?
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Methyl 3-amino-2-thiophenecarboxylate is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask (N95), eyeshields, and gloves. Ensure good ventilation.
Is Methyl 3-amino-2-thiophenecarboxylate available for export?
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Yes, Tech Serve Solutions, a specialist global supplier and exporter, can provide Methyl 3-amino-2-thiophenecarboxylate. Contact us for your export requirements.
How can I request a sample or quote for Methyl 3-amino-2-thiophenecarboxylate?
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Please use the contact form on our website or call us directly to request a sample or a quote for Methyl 3-amino-2-thiophenecarboxylate.
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