Methyl 3-amino-2-(trifluoromethyl)propionate
Methyl 3-amino-2-(trifluoromethyl)propionate (CAS: 914203-47-7) is a trifluoromethyl-containing building block with the formula H2NCH2CH(CF3)CO2CH3 and a molecular weight of 171.12 g/mol. This ester derivative is valuable in organic synthesis, particularly for introducing trifluoromethyl groups into complex molecules. Its primary applications lie in the research and development of novel chemical entities, pharmaceuticals, and agrochemicals, leveraging its unique structural features.
- IUPAC
- Methyl 2-(aminomethyl)-3,3,3-trifluoro-propanoate
Organic Synthesis Intermediate
Serves as a key building block in the synthesis of more complex organic molecules. The trifluoromethyl group imparts unique electronic and lipophilic properties, making it valuable for medicinal chemistry and materials science research.
Pharmaceutical Research and Development
Utilised in the development of new drug candidates. The presence of the CF3 group can significantly influence a molecule's metabolic stability, bioavailability, and binding affinity.
Agrochemical Innovation
A potential intermediate in the synthesis of novel pesticides and herbicides, where fluorinated compounds often exhibit enhanced efficacy and targeted activity.
Fluorine Chemistry Reagent
Employed in academic and industrial laboratories for exploring new synthetic methodologies and creating novel fluorinated compounds.
| Molecular weight | 171.12 |
|---|---|
| Linear formula | H2NCH2CH(CF3)CO2CH3 |
| Assay | 90% |
| Boiling point | 50 °C/0.2 mmHg |
| Density | 1.345 g/mL at 25 °C |
| Refractive index | n20/D 1.374 |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3-amino-2-(trifluoromethyl)propionate used for?
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Methyl 3-amino-2-(trifluoromethyl)propionate is primarily used as a building block in organic synthesis, particularly in the research and development of pharmaceuticals, agrochemicals, and novel fluorinated compounds.
What is the CAS number and chemical formula?
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The CAS number is 914203-47-7 and the chemical formula is H2NCH2CH(CF3)CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3-amino-2-(trifluoromethyl)propionate with an assay of 90%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Methyl 3-amino-2-(trifluoromethyl)propionate be handled safely?
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This compound is a Danger (GHS05, GHS07) with hazards H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Always use with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Refer to the safety data sheet for full handling instructions.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and Methyl 3-amino-2-(trifluoromethyl)propionate can be shipped internationally.
How can I request a sample or quote?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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