MES
MES (CAS 4432-31-9), with the molecular formula C6H13NO4S and a molecular weight of 195.24 g/mol, is a zwitterionic N-substituted aminosulfonic acid. It functions as a biological buffer, maintaining stable pH conditions in various biochemical and biological research applications. Its low UV absorbance and minimal metal ion binding make it suitable for sensitive assays. This ELITE quality product is commonly used in diagnostic assay manufacturing.

Biological Buffering Agent
MES is employed to maintain stable pH levels in biological research, enzymatic assays, and cell culture media. Its pKa of 6.1 and useful pH range of 5.5-6.7 make it ideal for applications requiring mildly acidic to neutral conditions.
Diagnostic Assay Manufacturing
This compound is a key reagent in the manufacturing of diagnostic assays. Its consistent purity and buffering capacity ensure reliable performance in sensitive in-vitro diagnostic products.
Electrophoresis and Chromatography
MES can be utilized as a buffer component in electrophoresis and chromatography techniques where precise pH control is critical for separating biomolecules.
| Molecular weight | 195.24 |
|---|---|
| Empirical formula | C6H13NO4S |
| Assay | ≥99% (titration) |
| pH | 2.5-4.0 (25 °C in neat) |
| Concentration | 0.5 M in H2O |
| Impurities tested | ≤1.0% water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Anion traces | chloride (Cl-): ≤10 mg/kgsulfate (SO42-): ≤10 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | ELITE |
|---|---|
| Pka  | 6.1 |
| Market Segment | Diagnostic Assay Manufacturing |
| Uv Absorption | λ: 260 nm Amax: 0.01λ: 280 nm Amax: 0.01 |
| Useful Ph Range | 5.5 - 6.7 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is MES used for?
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MES is primarily used as a biological buffer in research and diagnostic assay manufacturing, maintaining pH in the range of 5.5-6.7.
What are the CAS number and formula for MES?
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The CAS number for MES is 4432-31-9, and its molecular formula is C6H13NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies MES at an ELITE quality level with an assay of ≥99% by titration. It is not represented as USP, BP, or EP grade.
How should MES be handled safely?
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Handle MES with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation, and use a type N95 (US) or type P1 (EN143) respirator filter if dust is generated. Refer to the Safety Data Sheet for full handling precautions.
Is MES a controlled substance?
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The provided data does not indicate that MES is a controlled substance.
How is MES packed and shipped?
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MES is packed and exported by Tech Serve Solutions adhering to international shipping regulations for chemicals.
How can I request a sample or quote for MES?
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To request a sample or quote for MES, please contact the Tech Serve Solutions sales team via our website or designated contact channels.
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