LY225910
LY225910 (CAS: 133040-77-4), with the molecular formula C27H24BrN3O2 and a molecular weight of 502.40, is a cholecystokinin receptor antagonist. This off-white powder is primarily utilised in research settings for its role in studying cell signaling pathways and as a potential therapeutic agent. It serves as a valuable tool for neuroscientific research and the investigation of GPCR modulators.
- IUPAC
- 2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-4-(3H)-quinazolinone

Cholecystokinin Receptor Antagonist Research
LY225910 acts as a selective antagonist for cholecystokinin receptors, making it an important compound for researchers investigating the roles of CCK in physiological and pathological processes, particularly within the central nervous system.
Neuroscience and Cell Signaling Studies
This chemical is employed in studies related to neuroscience and cell signaling, offering insights into neuropeptide function and the modulation of G-protein coupled receptors (GPCRs).
Drug Discovery and Development
As an approved therapeutic candidate, LY225910 is a valuable reagent for drug discovery programs, especially those focused on developing treatments for conditions involving CCK receptor pathways.
| Molecular weight | 502.40 |
|---|---|
| Empirical formula | C27H24BrN3O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P301IF SWALLOWED
| Flash point | 337 - 405 °C / 638.6 - 761 °F |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is LY225910 used for?
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LY225910 is primarily used in research as a cholecystokinin receptor antagonist for studies in neuroscience, cell signaling, and drug discovery.
What are the CAS number and formula for LY225910?
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The CAS number for LY225910 is 133040-77-4, and its molecular formula is C27H24BrN3O2.
What grade and purity does Tech Serve Solutions supply for LY225910?
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Tech Serve Solutions supplies LY225910 with a purity of ≥98% (HPLC). This product is intended for research use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should LY225910 be handled and stored?
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LY225910 is classified as acutely toxic (Danger, H301) and may cause long lasting harmful effects to aquatic life (H413). It should be handled with appropriate personal protective equipment in a well-ventilated area. Store refrigerated at 2-8°C.
How is LY225910 packed, shipped, and exported?
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LY225910 is packed as an off-white powder and is shipped according to relevant dangerous goods regulations (UN 2811 6.1 / PGIII). TSS exports globally.
How can I request a sample or quote for LY225910?
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To request a sample or quote for LY225910, please contact our sales team through the website or by phone, referencing the product name and CAS number.
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