7-Dehydrocholesterol
7-Dehydrocholesterol (CAS: 434-16-2), with the molecular formula C27H44O and a molecular weight of 384.64 g/mol, is a vital sterol involved in cellular processes. It serves as a key intermediate in the biosynthesis of Vitamin D3 and plays a role in cholesterol metabolism. This compound is utilised in biochemical research, particularly in studies concerning lipid metabolism, cell signalling, and endocrinology. Tech Serve Solutions supplies 7-Dehydrocholesterol for research and development purposes.
- IUPAC
- (−)-7-Dehydrocholesterol,3β-Hydroxy-5,7-cholestadiene,5,7-Cholestadien-3β-ol,Provitamin D3
- Synonyms
- 5,7-Cholestadien-3β-ol3β-Hydroxy-5,7-cholestadieneProvitamin D3(–)-7-Dehydrocholesterol
Vitamin D3 Biosynthesis
7-Dehydrocholesterol is the direct precursor to Vitamin D3 (cholecalciferol) in the skin, formed via photolysis by ultraviolet B radiation. It is a critical intermediate in this metabolic pathway.
Cholesterol Metabolism Research
As a close analogue of cholesterol, 7-Dehydrocholesterol is employed in studies investigating cholesterol biosynthesis, transport, and metabolism within cells. Its role in cellular lipid regulation is a key area of research.
Cell Biology and Signalling
This compound finds application in cell biology research to explore its influence on cell membranes, lipid rafts, and various cell signalling pathways, particularly those involving sterols.
Endocrinology Studies
Due to its direct link to Vitamin D synthesis, 7-Dehydrocholesterol is a valuable tool for researchers studying endocrine functions and the hormonal roles of sterols and their derivatives.
| Molecular weight | 384.64 |
|---|---|
| Empirical formula | C27H44O |
| Assay | ≥95.0% (HPLC) |
| Optical activity | [α]20/D −116±6°, c = 1% in chloroform |
| Storage temperature | −20°C |
| Melting point | 148-152 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Dehydrocholesterol used for?
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7-Dehydrocholesterol is primarily used as a precursor in the biosynthesis of Vitamin D3 and in research related to cholesterol metabolism, cell biology, and endocrinology.
What are the CAS number and formula for 7-Dehydrocholesterol?
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The CAS number for 7-Dehydrocholesterol is 434-16-2, and its molecular formula is C27H44O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 7-Dehydrocholesterol with an assay of ≥95.0% (HPLC). This product is intended for research and development and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 7-Dehydrocholesterol be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C.
Is 7-Dehydrocholesterol a controlled substance?
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The provided data does not indicate that 7-Dehydrocholesterol is a controlled substance.
How is 7-Dehydrocholesterol packed and shipped?
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7-Dehydrocholesterol is packed and exported by Tech Serve Solutions according to industry best practices for chemical compounds, ensuring safe transit. Specific packaging details can be discussed upon inquiry.
How can I request a quote or sample?
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To request a quote or sample of 7-Dehydrocholesterol, please contact our sales team through the website or by phone, referencing the product CAS number 434-16-2.
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