7,8-Dihydroxyflavone hydrate
7,8-Dihydroxyflavone hydrate (CAS 38183-03-8) is a potent agonist of the tyrosine kinase receptor B (TrkB). With a molecular weight of 254.24 g/mol on an anhydrous basis, this compound is supplied as a solid with an assay of ≥98% (HPLC). It is primarily utilised in research for its ability to activate TrkB-mediated cell signalling pathways. These pathways are crucial in understanding neuroprotection, memory, and cardiovascular functions, including its potential role in studying Alzheimer's-like pathologies.
- Synonyms
- 7,8-DHF
Neuroscience Research
Acts as a selective TrkB agonist to investigate neurotrophic factor signalling, crucial for neuronal survival, growth, and function. It may be used to study its effects on Alzheimer-like dysfunction induced by scopolamine.
Cell Biology Studies
Investigates TrkB-mediated cell signalling pathways involved in processes such as memory formation and vasorelaxation. Useful for differentiating physiological effects of TrkB activation.
Pharmacological Research
Serves as a research tool to explore the therapeutic potential of TrkB activation in conditions related to neurodegeneration and hypertension.
| Molecular weight | 254.24 (anhydrous basis) |
|---|---|
| Empirical formula | C15H10O4 · xH2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | DMSO: soluble24 mg/mL |
| Storage temperature | room temp |
| Application | 7,8-Dihydroxyflavone (7,8-DHF), a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension. 7,8-Dihydroxyflavone may be used to study its effects on scopolamine induced Alzheimer-like pathologic dysfunction. |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7,8-Dihydroxyflavone hydrate used for?
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7,8-Dihydroxyflavone hydrate is used in research as a selective tyrosine kinase receptor B (TrkB) agonist to study neuroprotection, memory, vasorelaxation, hypertension, and its effects on Alzheimer-like pathology.
What is the CAS number and formula for 7,8-Dihydroxyflavone hydrate?
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The CAS number for 7,8-Dihydroxyflavone hydrate is 38183-03-8 (anhydrous basis). The empirical formula is C15H10O4 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 7,8-Dihydroxyflavone hydrate with a purity of ≥98% (HPLC). This product is intended for research use and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling guidelines for 7,8-Dihydroxyflavone hydrate?
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7,8-Dihydroxyflavone hydrate is classified with the GHS symbol GHS07 and a signal word of Warning, bearing the hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is 7,8-Dihydroxyflavone hydrate shipped and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ships and exports chemicals including 7,8-Dihydroxyflavone hydrate worldwide, adhering to all relevant shipping and export regulations.
How can I request a quote or sample for 7,8-Dihydroxyflavone hydrate?
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To request a quote or sample of 7,8-Dihydroxyflavone hydrate, please contact our sales team via the website or directly through our listed contact details.
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