Latrunculin B from Latruncula magnifica

CAS 76343-94-7C20H29NSO5Cell Biology

Latrunculin B (CAS: 76343-94-7), a potent actin inhibitor with the molecular formula C20H29NSO5 and a molecular weight of 395.51 g/mol, is a naturally occurring compound isolated from the marine sponge Latruncula magnifica. It functions by binding to G-actin, preventing its polymerisation into filaments. This characteristic makes Latrunculin B a valuable research tool in cell biology for investigating the dynamics of the cytoskeleton and cellular processes dependent on actin.

IUPAC: LAT-B

Email us

Latrunculin B from Latruncula magnifica (C20H29NSO5) — chemical structure, CAS 76343-94-7; Life Science, fine chemical supplied by Tech Serve Solutions

Actin Inhibitors and ProbesBioactive Small MoleculesCell BiologySpongeToxins and Venoms More...

01 /Applications

Cytoskeletal Research

Latrunculin B is widely employed to disrupt actin polymerisation, enabling researchers to study the roles of the actin cytoskeleton in various cellular functions such as cell motility, division, and morphology.

Cell Biology Investigations

As a specific inhibitor of actin, this compound serves as an essential reagent for probing cellular signalling pathways, cell shape regulation, and intracellular transport mechanisms dependent on cytoskeletal organisation.

Drug Discovery and Development

Its potent biological activity makes Latrunculin B a subject of interest in studies exploring therapeutic targets related to cellular dynamics and cancer research, although it is not approved for clinical use.

02 /Properties

Molecular weight	395.51
Empirical formula	C20H29NSO5
Assay	≥80% (HPLC)
Form	solid
Solubility	ethanol: soluble
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

76343-94-7

MDL number

MFCD00270879

05 /Additional specifications

Mol Wt	mol wt 395.5

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Latrunculin B used for?

Latrunculin B is primarily used as a research tool in cell biology to inhibit actin polymerisation, facilitating studies on the cytoskeleton, cell motility, cell division, and related cellular processes.

What is the CAS number and formula for Latrunculin B?

The CAS number for Latrunculin B is 76343-94-7, and its molecular formula is C20H29NSO5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Latrunculin B with an assay of ≥80% by HPLC. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.

What are the safety considerations when handling Latrunculin B?

When handling Latrunculin B, it is essential to use personal protective equipment including eyeshields and gloves. A respirator filter (type N95 or P1) should be used in environments where airborne particles may be present. The compound is classified under WGK 2 in Germany, indicating a hazard to water.

How is Latrunculin B stored and shipped?

Latrunculin B should be stored at -20°C. It is supplied as a solid and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for research chemicals.

How can I request a sample or quote for Latrunculin B?

To request a sample or a quotation for Latrunculin B, please contact the Tech Serve Solutions sales department via our website or direct email, providing your specific requirements.