Letrozole

CAS 112809-51-5C17H11N5Cell Biology

Letrozole (CAS: 112809-51-5), a non-steroidal aromatase inhibitor with the molecular formula C17H11N5 and a molecular weight of 285.30 g/mol, is primarily used in scientific research. It functions by blocking the aromatase enzyme, thereby reducing oestrogen production. This compound is valuable in cellular and hormonal studies, particularly in areas related to cell signalling and hormone-dependent research.

IUPAC: 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
Synonyms: 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile

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Letrozole (C17H11N5) — chemical structure, CAS 112809-51-5; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Aromatase Inhibition Research

Letrozole serves as a crucial tool in research settings to investigate the role of oestrogen and the aromatase enzyme in various biological processes. Its ability to significantly reduce oestrogen levels makes it invaluable for studying hormone-dependent cellular functions and signalling pathways.

Cell Signalling and Neuroscience Studies

This compound is employed in advanced research within cell signalling and neuroscience. Researchers utilise Letrozole to explore the intricate mechanisms by which oestrogen influences neuronal activity and brain function.

Hormonal Research Tool

As a potent inhibitor of aromatase, Letrozole is essential for studies focusing on hormonal regulation and the impact of reduced oestrogen levels. It aids in understanding endocrine system functions and related physiological effects.

Approved Therapeutics Research

Letrozole is recognised in the field of approved therapeutics and drug candidates. Its mechanism of action is studied for its implications in developing or understanding treatments related to hormone-dependent conditions.

02 /Properties

Molecular weight	285.30
Empirical formula	C17H11N5
Assay	≥98% (HPLC)
Form	powder
Colour	white to off-white
Solubility	DMSO: >50 mg/mL
Storage temperature	2-8°C

03 /Identifiers & registry

CAS number

112809-51-5

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Letrozole primarily used for?

Letrozole is primarily used in scientific research as an aromatase inhibitor to study oestrogen synthesis, cell signalling, hormonal regulation, and related biological processes.

What are the CAS number and molecular formula for Letrozole?

The CAS number for Letrozole is 112809-51-5, and its molecular formula is C17H11N5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Letrozole with an assay of ≥98% by HPLC. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.

How should Letrozole be handled and stored?

Letrozole is classified as hazardous (WGK Germany: 3). Handle with appropriate personal protective equipment in a well-ventilated area. Store at 2-8°C.

How is Letrozole packed, shipped, and exported?

Letrozole is typically supplied as a white to off-white powder and is carefully packaged for secure domestic and international shipment, adhering to all relevant regulations for chemical export.