Lercanidipine hydrochloride hemihydrate
Lercanidipine hydrochloride hemihydrate (CAS: 132866-11-6) is a dihydropyridine calcium channel blocker with the chemical formula C36H41N3O6 · HCl · 0.5H2O and a molecular weight of 657.20. This yellow powder is primarily utilised in research settings as a tool to study voltage-gated ion channels and cellular signalling pathways. Its specific action on calcium channels makes it a valuable compound for investigating cardiovascular and neurological processes.
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Calcium Channel Modulation Research
Lercanidipine hydrochloride hemihydrate serves as a potent modulator of L-type calcium channels. Researchers utilise this compound to investigate the physiological roles of calcium influx in various cell types, including cardiac and smooth muscle cells.
Cellular Signalling Studies
This chemical is employed in studies exploring cell signalling cascades, particularly those influenced by calcium ions. Its effects on cellular processes are of interest in understanding cell biology and neuroscience research.
Drug Discovery and Development
As an approved therapeutic agent, Lercanidipine hydrochloride hemihydrate is available for preclinical research and development purposes. It aids in the validation of new therapeutic targets related to calcium channel function.
| Molecular weight | 657.20 |
|---|---|
| Empirical formula | C36H41N3O6 · HCl · 0.5H2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccatedprotect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lercanidipine hydrochloride hemihydrate used for?
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Lercanidipine hydrochloride hemihydrate is used in research settings to study voltage-gated ion channels, cellular signalling, and as a tool for investigating cardiovascular and neurological processes. It is also an approved therapeutic agent, making it relevant for drug discovery research.
What is the CAS number and chemical formula for Lercanidipine hydrochloride hemihydrate?
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The CAS number for Lercanidipine hydrochloride hemihydrate (anhydrous) is 132866-11-6. The chemical formula is C36H41N3O6 · HCl · 0.5H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Lercanidipine hydrochloride hemihydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product documentation.
How should Lercanidipine hydrochloride hemihydrate be handled?
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Lercanidipine hydrochloride hemihydrate is classified as toxic if swallowed (H301) and requires careful handling. Use with adequate ventilation and wear appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Store in a desiccated, light-protected environment at 2-8°C.
Is Lercanidipine hydrochloride hemihydrate a controlled substance?
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The provided data does not indicate that Lercanidipine hydrochloride hemihydrate is a controlled substance.
How is Lercanidipine hydrochloride hemihydrate packed and shipped?
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Lercanidipine hydrochloride hemihydrate is typically supplied as a yellow powder. It is shipped according to UN 2811, Class 6.1, Packing Group III regulations, suitable for international export.
How can I request a sample or quote for Lercanidipine hydrochloride hemihydrate?
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To request a sample or a quote, please contact our sales team through the TSS website or by telephone, providing the product name and CAS number.
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