Latrunculin A
Latrunculin A (CAS: 76343-93-6), a unique molecule with the formula C22H31NO5S and a molecular weight of 421.55 g/mol, is a potent inhibitor of actin polymerization. Derived from marine sponges, this waxy solid compound plays a crucial role in cell biology research by disrupting the cytoskeleton. Its primary applications lie in scientific investigations related to cell structure, cell motility, and intracellular transport mechanisms.
- IUPAC
- LAT-A,[1R-[1R*, 4Z, 8E, 10Z, 12S*, 15R*, 17R*(R*)]]-4-(17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone

Actin Polymerization Inhibition
Latrunculin A binds to G-actin monomers, preventing their incorporation into growing actin filaments. This makes it an invaluable tool for studying the dynamic regulation of the actin cytoskeleton in various cellular processes.
Cytoskeleton Research
By depolymerizing actin filaments, Latrunculin A is widely used to investigate the roles of actin in cell shape, cell division, intracellular transport, and cell migration.
Cell Biology Studies
This compound serves as a critical reagent for researchers exploring fundamental cellular functions and signaling pathways that involve the actin cytoskeleton. Its specific mechanism allows for precise experimental manipulation.
Tool in Neuroscience Research
Latrunculin A can be applied to study the role of actin dynamics in neuronal development, synaptic plasticity, and other neuroscience-related cellular events.
| Molecular weight | 421.55 |
|---|---|
| Empirical formula | C22H31NO5S |
| Assay | ≥85% (HPLC) |
| Form | waxy solid |
| Solubility | DMSO: solubleethanol: soluble |
| Storage temperature | −20°C |
| Biological source | from sea sponge |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt 421.6 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Latrunculin A used for?
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Latrunculin A is primarily used as a research tool to inhibit actin polymerization, enabling studies on cytoskeleton dynamics, cell shape, cell motility, and intracellular transport.
What is the CAS number and formula for Latrunculin A?
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The CAS number for Latrunculin A is 76343-93-6, and its molecular formula is C22H31NO5S.
What grade and purity does Tech Serve Solutions supply for Latrunculin A?
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Tech Serve Solutions supplies Latrunculin A with an assay of ≥85% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Latrunculin A be handled and stored?
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Handle Latrunculin A with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the compound at −20°C.
Is Latrunculin A a controlled substance?
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The provided data does not indicate that Latrunculin A is a controlled substance.
How is Latrunculin A packed and shipped?
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Latrunculin A is available as a waxy solid. Packaging and shipping methods adhere to regulations for chemical export, ensuring product integrity and safety during transit.
How can I request a quote or sample for Latrunculin A?
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To request a quote or sample of Latrunculin A, please contact the Tech Serve Solutions sales team through our website or by phone.
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