L-Leucine β-naphthylamide
L-Leucine β-naphthylamide (CAS: 732-85-4) is a biochemical reagent with the molecular formula C16H20N2O and a molecular weight of 256.34 g/mol. This compound serves as a crucial substrate for the determination of leucine aminopeptidase activity. It is primarily employed in both colorimetric assays and histochemical staining procedures for the detection and quantification of this enzyme.
- IUPAC
- L-Leucine-2-naphthylamide
- Synonyms
- L-Leucine-2-naphthylamide
Enzyme Substrate for Leucine Aminopeptidase
L-Leucine β-naphthylamide functions as a chromogenic substrate for the enzyme leucine aminopeptidase. Its hydrolysis by the enzyme releases β-naphthylamine, which can be detected colorimetrically.
Histochemical Staining
This compound is utilised in histochemical techniques to localise and visualise leucine aminopeptidase activity within tissue sections. The insoluble nature of the reaction product aids in precise localisation.
Biochemical Research
Used in research settings to study enzyme kinetics, develop diagnostic assays, and investigate the role of leucine aminopeptidase in biological processes.
| Molecular weight | 256.34 |
|---|---|
| Empirical formula | C16H20N2O |
| Solubility | H2O: insoluble |
| Storage temperature | −20°C |
| Application | Substrate for leucine aminopeptidase determination in colorimetric and histochemical procedures. |
Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Leucine β-naphthylamide used for?
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L-Leucine β-naphthylamide (CAS: 732-85-4) is used as a substrate for determining leucine aminopeptidase activity in colorimetric assays and histochemical procedures.
What are the CAS number and formula for L-Leucine β-naphthylamide?
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The CAS number is 732-85-4 and the empirical formula (Hill notation) is C16H20N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Leucine β-naphthylamide for research and technical applications. The specific grade and purity are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
How should L-Leucine β-naphthylamide be handled safely?
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L-Leucine β-naphthylamide is classified with GHS08 symbol and a 'Warning' signal word, carrying hazard statement H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields, gloves, and a P100 respirator (US) or P3 (EN143) filter, must be used. Handle in a well-ventilated area or fume hood.
Is L-Leucine β-naphthylamide a controlled substance?
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The provided safety data does not indicate that L-Leucine β-naphthylamide is a controlled substance.
How is L-Leucine β-naphthylamide packed and exported?
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This chemical is typically stored at -20°C. TSS is an experienced global supplier and exporter, adhering to all regulations for the safe packing and international shipment of fine chemicals.
How can I request a quote or sample?
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Please contact our sales team via the website or directly by phone to request a quote or a sample of L-Leucine β-naphthylamide.
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