3,4-Dimethoxybenzaldehyde
3,4-Dimethoxybenzaldehyde (CAS: 120-14-9) is an organic compound with the linear formula (CH₃O)₂C₆H₃CHO and a molecular weight of 166.17 g/mol. This aromatic aldehyde, often referred to as veratraldehyde, is a key intermediate in organic synthesis. It is frequently employed as a building block in the preparation of more complex molecules, including those with potential pharmaceutical activity. Its aldehyde functional group allows for versatile chemical transformations.
- IUPAC
- Vanillin methyl ether,Veratraldehyde
- Synonyms
- (CH3O)2C6H3CHOVeratraldehydeVanillin methyl ether
Synthesis of Dioxolane Derivatives
3,4-Dimethoxybenzaldehyde serves as a precursor in the synthesis of specific dioxolane compounds, such as 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane. This application highlights its utility in forming heterocyclic structures.
Preparation of Biologically Active Molecules
The compound has been utilised in the synthesis of complex natural products, including (+)-lithospermic acid, which has demonstrated anti-HIV activity. This underscores its role in medicinal chemistry research.
Organic Synthesis Building Block
As a readily available aromatic aldehyde, 3,4-Dimethoxybenzaldehyde functions as a fundamental building block in diverse organic synthesis pathways. Its structure allows for various derivatisations and condensations.
| Molecular weight | 166.17 |
|---|---|
| Linear formula | (CH3O)2C6H3CHO |
| Assay | 99% |
| Boiling point | 281 °C(lit.) |
| Solubility | alcohol: freely solublediethyl ether: freely solublewater: slightly soluble (hot) |
| Application | 3,4-Dimethoxybenzaldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane1. It was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity2. |
| Melting point | 40-43 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dimethoxybenzaldehyde used for?
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3,4-Dimethoxybenzaldehyde is primarily used as a building block in organic synthesis. It has been employed in the preparation of dioxolane derivatives and in the synthesis of molecules with potential biological activity, such as anti-HIV compounds.
What is the CAS number and formula for 3,4-Dimethoxybenzaldehyde?
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The CAS number is 120-14-9, and its linear formula is (CH₃O)₂C₆H₃CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dimethoxybenzaldehyde with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 3,4-Dimethoxybenzaldehyde be handled safely?
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3,4-Dimethoxybenzaldehyde is classified as a warning substance. It is harmful if swallowed (H302), causes skin irritation (H315), and causes serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation and avoid dust formation.
Is 3,4-Dimethoxybenzaldehyde available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3,4-Dimethoxybenzaldehyde.
How can I request a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quote or a sample of 3,4-Dimethoxybenzaldehyde.
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