3,4-Dimethoxybenzoyl chloride
3,4-Dimethoxybenzoyl chloride (CAS 3535-37-3) is an organic compound with the linear formula (CH3O)2C6H3COCl and a molecular weight of 200.62 g/mol. This acid halide serves as a valuable intermediate and building block in organic synthesis. It is primarily employed in the chemical industry for the creation of complex molecules, including pharmaceutical intermediates and research chemicals. Its reactivity makes it a useful reagent for introducing the 3,4-dimethoxybenzoyl group into various organic structures.
- IUPAC
- Veratroyl chloride
- Synonyms
- Veratroyl chloride
Synthesis of Oxazole Derivatives
3,4-Dimethoxybenzoyl chloride has been utilised in the synthesis of specific oxazole derivatives, such as (+)-5-(3,4-dimethoxyphenyl)-4-[[N-[(4S)-2-oxo-4-(phenylmethyl)-2-oxazolidinyl]]carbonyl] oxazole and its enantiomer.
Preparation of Benzamide Compounds
This acid chloride is employed in the preparation of substituted benzamides. An example includes its use in the synthesis of N-(2,5-dibromophenyl)-3,4-dimethoxybenzamide.
Organic Synthesis Building Block
As a reactive carbonyl compound, 3,4-Dimethoxybenzoyl chloride functions as a key building block in various organic synthesis pathways, enabling the construction of more complex molecular architectures.
| Molecular weight | 200.62 |
|---|---|
| Linear formula | (CH3O)2C6H3COCl |
| Assay | ≥97.0% (AT) |
| Application | 3,4-Dimethoxybenzoyl chloride has been used in synthesis of:• (+)-5-(3,4-dimethoxyphenyl)-4-[[N-[(4S)-2-oxo-4-(phenylmethyl)-2-oxazolidinyl]]carbonyl] oxazole and its enantiomer1• N-(2,5-dibromophenyl)-3,4-dimethoxybenzamide2 |
| Melting point | 70-73 °C(lit.)70-73 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dimethoxybenzoyl chloride used for?
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3,4-Dimethoxybenzoyl chloride is used as a building block in organic synthesis, particularly for creating complex molecules such as specific oxazole derivatives and substituted benzamides, often serving as an intermediate in chemical research and development.
What is the CAS number and formula for 3,4-Dimethoxybenzoyl chloride?
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The CAS number is 3535-37-3, and its linear formula is (CH3O)2C6H3COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dimethoxybenzoyl chloride with an assay of ≥97.0% (AT). We do not represent this product as USP, BP, or EP grade.
How should 3,4-Dimethoxybenzoyl chloride be handled?
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3,4-Dimethoxybenzoyl chloride is a hazardous substance (GHS05, Danger, H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 filter), must be used. Handle only in a well-ventilated area.
Is 3,4-Dimethoxybenzoyl chloride a controlled substance?
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The provided data does not indicate that 3,4-Dimethoxybenzoyl chloride is a controlled substance.
How is 3,4-Dimethoxybenzoyl chloride exported and shipped?
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3,4-Dimethoxybenzoyl chloride is classified under UN 3261, Hazard Class 8, Packing Group II. Tech Serve Solutions exports and ships this chemical in compliance with all relevant regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or a sample of 3,4-Dimethoxybenzoyl chloride, please contact our sales department through the website or via direct inquiry, providing your specific requirements.
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