Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate
Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate (CAS: 391-02-6; Formula: C13H10F3NO3) is a heterocyclic building block with a molecular weight of 285.22 g/mol. It is a key intermediate in organic synthesis, particularly within the quinoline class of compounds. This chemical is suitable for various research and development applications, serving as a versatile component in the construction of more complex molecular structures for diverse chemical studies.

Organic Synthesis Intermediate
Utilised as a foundational building block in multi-step organic syntheses. Its trifluoromethyl and quinoline functionalities offer unique reactivity for creating novel chemical entities.
Medicinal Chemistry Research
Serves as a precursor in the development of potential pharmaceutical agents. The quinoline scaffold is prevalent in many biologically active molecules, making this compound of interest for drug discovery programs.
Materials Science Exploration
Can be incorporated into novel materials requiring specific electronic or structural properties. The trifluoromethyl group can influence solubility and electronic characteristics.
| Molecular weight | 285.22 |
|---|---|
| Empirical formula | C13H10F3NO3 |
| Assay | 95% |
| Melting point | >300 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylate used for?
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This compound is primarily used as a building block in organic synthesis, particularly for the creation of novel quinoline derivatives, and is of interest in medicinal chemistry research and materials science exploration.
What are the CAS number and formula for this product?
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The CAS number is 391-02-6, and the empirical formula (Hill notation) is C13H10F3NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 95%. We do not represent it as USP, BP, EP, or pharmacopoeia grade.
What are the main safety hazards associated with this chemical?
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This compound is classified with GHS07 symbol and the signal word 'Warning'. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product, and can facilitate international orders.
How can I request a sample or a quote?
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To request a sample or a quote, please contact our sales team through the website or by calling the provided phone number, quoting the product name and CAS number.
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