3,4-Dimethoxybenzylzinc chloride solution
3,4-Dimethoxybenzylzinc chloride solution (CAS: 307531-79-9) is an organozinc reagent with the linear formula (CH3O)2C6H3CH2ZnCl and a molecular weight of 252.03 g/mol. Supplied as a 0.5 M solution in THF, this compound is primarily utilised in organic synthesis as a versatile nucleophilic coupling partner. Its reactivity makes it suitable for introducing the 3,4-dimethoxybenzyl group into various organic molecules, facilitating complex molecular construction.
- Synonyms
- (CH3O)2C6H3CH2ZnCl
Organozinc Reagent in Cross-Coupling Reactions
This compound serves as an effective nucleophile in various transition metal-catalysed cross-coupling reactions, such as Negishi couplings. It enables the formation of new carbon-carbon bonds by reacting with organic halides or pseudohalides.
Synthesis of Pharmaceutical Intermediates
The 3,4-dimethoxybenzyl moiety is present in numerous biologically active compounds. This reagent can be employed in the synthesis of complex organic molecules, including intermediates for pharmaceuticals and fine chemicals.
Functionalisation of Organic Scaffolds
3,4-Dimethoxybenzylzinc chloride solution allows for the regioselective and stereoselective introduction of the 3,4-dimethoxybenzyl group onto diverse organic scaffolds, aiding in the development of novel chemical entities.
| Molecular weight | 252.03 |
|---|---|
| Linear formula | (CH3O)2C6H3CH2ZnCl |
| Boiling point | 65 °C |
| Density | 0.968 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
- P422
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dimethoxybenzylzinc chloride solution used for?
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3,4-Dimethoxybenzylzinc chloride solution is used as an organozinc reagent in organic synthesis, particularly for cross-coupling reactions and the introduction of the 3,4-dimethoxybenzyl group into organic molecules for the synthesis of complex compounds and pharmaceutical intermediates.
What are the CAS number and formula for this product?
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The CAS number for 3,4-Dimethoxybenzylzinc chloride solution is 307531-79-9, and its linear formula is (CH3O)2C6H3CH2ZnCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. The specific purity or assay is not detailed beyond its solution concentration. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
How should 3,4-Dimethoxybenzylzinc chloride solution be handled safely?
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This compound is flammable and reacts violently with water, posing significant risks. It can also cause skin and eye irritation and may be a respiratory irritant and suspected carcinogen. Handle under an inert atmosphere, away from ignition sources, and avoid contact with water. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,4-Dimethoxybenzylzinc chloride solution.
How can I request a quote or sample?
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To request a quote or sample of 3,4-Dimethoxybenzylzinc chloride solution, please contact the Tech Serve Solutions sales team through the website or by phone.
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