2-Aminopurine
2-Aminopurine (CAS 452-06-2), with the molecular formula C5H5N5 and a molecular weight of 135.13 g/mol, is a biochemical compound. It is primarily utilised for its specific inhibitory action on double-stranded RNA-dependent protein kinase, specifically protein kinase R (PKR). This targeted biological activity makes it a valuable reagent in biochemical research and molecular biology studies.
- IUPAC
- 2-AP
PKR Inhibition
2-Aminopurine is employed as a selective inhibitor for double-stranded RNA-dependent protein kinase, commonly known as Protein Kinase R (PKR). This inhibition is crucial for studying the PKR pathway and its role in cellular processes.
Biochemical Research
As a nucleoside analogue, 2-Aminopurine serves as a valuable tool in various biochemical research applications. Its properties allow for the investigation of enzyme mechanisms and cellular signalling pathways.
Molecular Biology Studies
The compound is utilised in molecular biology to understand the functions of specific kinases and their impact on gene expression and protein synthesis.
| Molecular weight | 135.13 |
|---|---|
| Empirical formula | C5H5N5 |
| Assay | ≥99% |
| Storage temperature | 2-8°C |
| Application | 2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR). |
| Melting point | 280-282 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Aminopurine used for?
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2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR).
What is the CAS number and formula for 2-Aminopurine?
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The CAS number for 2-Aminopurine is 452-06-2, and its empirical formula is C5H5N5.
What grade and purity does Tech Serve Solutions supply for 2-Aminopurine?
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Tech Serve Solutions supplies 2-Aminopurine with a minimum assay of ≥99%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Aminopurine be handled safely?
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Handle 2-Aminopurine with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling information.
Is 2-Aminopurine supplied by Tech Serve Solutions for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Aminopurine.
How can I request a sample or quote for 2-Aminopurine?
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Please contact our sales team directly via the website or by phone to request a sample or a quotation for 2-Aminopurine.
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