L-Citrulline
L-Citrulline (CAS: 372-75-8; Formula: C6H13N3O3; Molar Mass: 175.19 g/mol) is a non-essential amino acid derivative. It plays a role in the urea cycle, assisting the body in eliminating ammonia. L-Citrulline is synthesised endogenously and also obtained through diet. It is widely utilised in chemical biology and synthesis research, as well as in peptide chemistry applications.
- IUPAC
- (S)-2-Amino-5-ureidopentanoic acid,L-2-Amino-5-ureidovaleric acid
- Synonyms
- (S)-2-Amino-5-ureidopentanoic acidL-2-Amino-5-ureidovaleric acid

Chemical Biology Research
L-Citrulline serves as a valuable compound in biological research, aiding studies related to amino acid metabolism and physiological pathways. Its role in the urea cycle makes it a subject of interest for understanding nitrogen excretion and detoxification processes.
Peptide Synthesis
As an unnatural amino acid derivative, L-Citrulline is incorporated into synthetic peptides. This allows for the modification of peptide structures and functions, expanding the scope of peptide-based research and development in various scientific fields.
Chemical Synthesis Applications
The compound is employed in diverse chemical synthesis processes. Its specific structural features and reactivity profile make it a useful building block or intermediate in the creation of more complex organic molecules for research purposes.
| Molecular weight | 175.19 |
|---|---|
| Empirical formula | C6H13N3O3 |
| Assay | 98% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Citrulline used for?
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L-Citrulline is used in chemical biology, chemical synthesis, peptide chemistry, and for the study of unnatural amino acid derivatives. It is also recognised for its role in the urea cycle for ammonia elimination.
What is the CAS number and formula for L-Citrulline?
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The CAS number for L-Citrulline is 372-75-8, and its empirical formula (Hill notation) is C6H13N3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Citrulline with an assay of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should L-Citrulline be handled safely?
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When handling L-Citrulline, it is essential to use safety precautions including eyeshields and gloves. A respirator filter, such as type N95 (US) or type P1 (EN143), should be used for respiratory protection.
Does Tech Serve Solutions export L-Citrulline?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including L-Citrulline, serving customers worldwide.
How can I request a quote or sample for L-Citrulline?
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To request a quote or sample of L-Citrulline, please contact our sales team through the website or by phone, providing your specific requirements.
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