Ethyl 4-chloro-4-oxobutyrate
Ethyl 4-chloro-4-oxobutyrate (CAS: 14794-31-1) is a reactive acid halide with the linear formula ClCOCH2CH2CO2C2H5 and a molecular weight of 164.59 g/mol. As an organic building block, it is employed in chemical synthesis for creating more complex molecules. Its utility is demonstrated in the preparation of polymer-supported catalysts, succinimidyl esters of polycyclic aromatic hydrocarbons, and prodrugs of curcuminoids.
- IUPAC
- Ethyl succinyl chloride
- Synonyms
- Ethyl succinyl chloride
Synthesis of Polymer-Supported Catalysts
Ethyl 4-chloro-4-oxobutyrate has been utilised as a key intermediate in the preparation of polymer-supported bifunctional catalysts, contributing to advancements in catalytic methodologies.
Preparation of Succinimidyl Esters
This compound serves as a reagent in the synthesis of succinimidyl esters, including those derived from polycyclic aromatic hydrocarbons like benzo(a)pyrene.
Development of Prodrugs
It finds application in the creation of succinate prodrugs, notably for curcuminoids, a class of compounds with significant biological interest.
| Molecular weight | 164.59 |
|---|---|
| Linear formula | ClCOCH2CH2CO2C2H5 |
| Assay | 95% |
| Boiling point | 88-90 °C/11 mmHg(lit.) |
| Density | 1.155 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.437(lit.) |
| Storage temperature | 2-8°C |
| Application | Ethyl 4-chloro-4-oxobutyrate was used in the synthesis of:• polymer-supported bifunctional catalyst1• succinimidyl ester of benzo(a)pyrene2• succinate prodrugs of curcuminoids2 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 84 °C / 183.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4-chloro-4-oxobutyrate used for?
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Ethyl 4-chloro-4-oxobutyrate is used as a building block in chemical synthesis, including the preparation of polymer-supported catalysts, succinimidyl esters, and prodrugs.
What are the CAS number and formula for Ethyl 4-chloro-4-oxobutyrate?
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The CAS number is 14794-31-1, and its linear formula is ClCOCH2CH2CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4-chloro-4-oxobutyrate with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Ethyl 4-chloro-4-oxobutyrate be handled safely?
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Ethyl 4-chloro-4-oxobutyrate is classified as Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including full-face respirators, gloves, and goggles, is essential. Handle in a well-ventilated area, and refer to the Safety Data Sheet for detailed handling instructions.
How is Ethyl 4-chloro-4-oxobutyrate typically packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions adheres to stringent packaging and shipping regulations for chemicals like Ethyl 4-chloro-4-oxobutyrate, including compliance with UN 3265, Class 8, Packing Group II for transportation.
How can I request a quote or sample?
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To request a quote or sample of Ethyl 4-chloro-4-oxobutyrate, please contact our sales department via the website or by phone.
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