Ethyl 4-chlorobutyrate
Ethyl 4-chlorobutyrate (CAS 3153-36-4, C6H11ClO2) is an ester of 4-chlorobutyric acid and ethanol, with a molecular weight of 150.60 g/mol. This organic compound is a valuable intermediate in chemical synthesis, particularly in the production of pharmaceuticals and other fine chemicals. It is characterised by its ester functional group and a terminal chlorine atom, allowing for diverse synthetic transformations. Tech Serve Solutions supplies this chemical for research and development purposes.

Pharmaceutical Intermediate
Ethyl 4-chlorobutyrate serves as a key building block in the synthesis of various active pharmaceutical ingredients (APIs). Its structure allows for straightforward incorporation into complex molecular architectures, facilitating drug discovery and development.
Organic Synthesis Reagent
This ester is widely employed in general organic synthesis. The presence of both an ester group and a reactive alkyl chloride moiety makes it a versatile reagent for introducing the 4-oxobutanoate or related fragments into target molecules.
Fine Chemical Production
It is utilized in the manufacturing of specialised fine chemicals. Its reactivity enables its use in multi-step syntheses for diverse applications, contributing to the supply chain of advanced chemical products.
| Molecular weight | 150.60 |
|---|---|
| Linear formula | Cl(CH2)3CO2C2H5 |
| Assay | ≥97.5% (GC) |
| Grade | purum |
| Boiling point | 186 °C(lit.) |
| Density | 1.075 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.432(lit.)n20/D 1.432 |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 76 °C / 168.8 °F |
| Transport (UN / ADR) | UN 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4-chlorobutyrate used for?
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Ethyl 4-chlorobutyrate is primarily used as an intermediate in pharmaceutical synthesis and a versatile reagent in organic and fine chemical production.
What is the CAS number and molecular formula for Ethyl 4-chlorobutyrate?
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The CAS number is 3153-36-4 and the molecular formula is Cl(CH2)3CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4-chlorobutyrate with a purity of ≥97.5% (GC) and a purum grade. We do not represent this product as USP, BP, or EP grade.
How should Ethyl 4-chlorobutyrate be handled safely?
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Ethyl 4-chlorobutyrate is harmful if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Ensure adequate ventilation, wear appropriate personal protective equipment including gloves and eye/face protection, and avoid breathing vapour or dust. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is Ethyl 4-chlorobutyrate a controlled substance?
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The provided data does not indicate that Ethyl 4-chlorobutyrate is a controlled substance.
How is Ethyl 4-chlorobutyrate shipped and exported?
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Ethyl 4-chlorobutyrate is shipped according to UN 1993 regulations as a flammable liquid, Class 3, Packing Group III. Tech Serve Solutions is experienced in global export.
How can I request a quote or sample?
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Please contact our sales team via the website or direct inquiry to request a quote or sample of Ethyl 4-chlorobutyrate.
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