Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate (CAS: 5909-24-0, C8H9ClN2O2S) is a pyrimidine derivative supplied by Tech Serve Solutions. With a molecular weight of 232.69 g/mol, this halogenated heterocyclic compound serves as a valuable building block in chemical synthesis. Its primary application lies in the preparation of novel pyrimidinopyridone structures, which have shown potential as FMS tyrosine kinase inhibitors. It is typically supplied with an assay of 98% and stored under refrigeration.
Synthesis of Pyrimidinopyridones
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate is utilized as a key intermediate in the synthesis of fused heterocyclic systems, specifically pyrimidinopyridones. These compounds are of interest in medicinal chemistry research.
FMS Tyrosine Kinase Inhibitor Research
Research has demonstrated the use of this pyrimidine carboxylate in the development of molecules investigated for their potential to inhibit FMS tyrosine kinase, a target relevant in various therapeutic areas.
Heterocyclic Building Block
As a functionalised pyrimidine, it offers reactive sites for further chemical transformations, making it a versatile building block for constructing more complex molecular architectures in organic synthesis.
| Molecular weight | 232.69 |
|---|---|
| Empirical formula | C8H9ClN2O2S |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Application | Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate was used in the synthesis of pyrimidinopyridones, potential inhibitors of the FMS tyrosine kinase1. |
| Melting point | 60-63 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate used for?
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Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate is primarily used as a building block in chemical synthesis, particularly for creating pyrimidinopyridone structures that have been investigated as potential FMS tyrosine kinase inhibitors.
What are the CAS number and chemical formula for Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate?
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The CAS number is 5909-24-0, and the chemical formula is C8H9ClN2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate be handled?
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This compound is a warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent). Ensure adequate ventilation and avoid dust formation.
How is this chemical packed and exported by TSS?
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Tech Serve Solutions exports chemicals globally. Specific packaging details for Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate depend on order quantity and destination, adhering to international shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate, please contact our sales department via the website or designated contact channels.
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