L-Azetidine-2-carboxylic acid
L-Azetidine-2-carboxylic acid (CAS: 2133-34-8), with the molecular formula C4H7NO2 and a molecular weight of 101.10 g/mol, is a non-proteinogenic amino acid. It serves as a valuable building block in organic synthesis, particularly in the development of novel pharmaceuticals and peptidomimetics. Its unique cyclic structure allows for the introduction of specific conformational constraints in target molecules, making it a key intermediate in chemical biology and drug discovery.
- IUPAC
- (S)-Azetidine-2-carboxylic acid

Pharmaceutical Intermediates
L-Azetidine-2-carboxylic acid is a key chiral building block for the synthesis of various pharmacologically active compounds. Its incorporation into molecular structures can confer desirable properties for drug candidates.
Peptide Chemistry
This unnatural amino acid is utilised in the design and synthesis of modified peptides and peptidomimetics. It allows for the exploration of novel peptide architectures with enhanced stability or specific biological activities.
Asymmetric Synthesis
As a chiral molecule, L-Azetidine-2-carboxylic acid finds application in asymmetric synthesis, enabling the creation of enantiomerically pure compounds. It can be used as a chiral auxiliary or a starting material for stereoselective transformations.
Chemical Biology Research
It is employed in chemical biology to probe biological systems and develop molecular tools. Its unique structural features can be leveraged to design probes for studying protein-protein interactions or enzyme mechanisms.
| Molecular weight | 101.10 |
|---|---|
| Empirical formula | C4H7NO2 |
| Assay | ≥98.0% (NT) |
| Grade | purum |
| Optical activity | [α]20/D −123±2°, c = 4% in H2O |
| Melting point | ~215 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Azetidine-2-carboxylic acid used for?
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L-Azetidine-2-carboxylic acid is primarily used as a building block in organic synthesis, particularly for pharmaceutical intermediates, peptide chemistry, and asymmetric synthesis. It is also valuable in chemical biology research.
What is the CAS number and molecular formula for L-Azetidine-2-carboxylic acid?
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The CAS number is 2133-34-8 and the molecular formula is C4H7NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Azetidine-2-carboxylic acid in 'purum' grade with an assay of ≥98.0% (NT). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling recommendations for L-Azetidine-2-carboxylic acid?
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Based on the provided safety information, appropriate personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK rating of 3 in Germany, indicating a significant hazard to water.
Does Tech Serve Solutions export L-Azetidine-2-carboxylic acid?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including L-Azetidine-2-carboxylic acid.
How can I request a sample or quote for L-Azetidine-2-carboxylic acid?
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To request a sample or quote for L-Azetidine-2-carboxylic acid, please contact our sales team through the website or via the provided contact details.
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