L-C-Propargylglycine
L-C-Propargylglycine (CAS: 23235-01-0; Formula: C5H7NO2; MW: 113.11) is a non-proteinogenic amino acid derivative offered by Tech Serve Solutions. This compound serves as a valuable reagent in chemical biology and synthesis, primarily for the irreversible inactivation of enzymes like γ-cystathionase. Its unique structure also allows for the creation of tritiated peptides with high specific radioactivity, making it useful in biochemical research and peptide chemistry.
- IUPAC
- (S)-2-Amino-4-pentynoic acid,L-Propargylglycine
Enzyme Inactivation
L-C-Propargylglycine acts as a reagent for the irreversible inactivation of enzymes, notably γ-cystathionase. This property is crucial for studying enzyme mechanisms and biological pathways.
Affinity Labelling
This compound can be employed as an affinity labelling reagent to identify and study enzymes such as γ-cystathionase. It selectively binds to the active site of target enzymes.
Peptide Synthesis
Peptides incorporating L-C-Propargylglycine can be tritiated to achieve high specific radioactivity. This is beneficial for radiolabelling studies in molecular biology and drug discovery.
| Molecular weight | 113.11 |
|---|---|
| Empirical formula | C5H7NO2 |
| Assay | ≥99.0% (TLC) |
| Storage temperature | 2-8°C |
| Application | Reagent for the irreversible inactivation of γ-cystathionase1,2; affinity labeling reagent for γ-cystathionase and other enzymes3; peptides containing this amino acid can be tritiated to high specific radioactivity4 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-C-Propargylglycine used for?
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L-C-Propargylglycine is used as a reagent for the irreversible inactivation of γ-cystathionase, as an affinity labelling reagent for enzymes, and in the synthesis of tritiated peptides for biochemical research.
What is the CAS number and formula for L-C-Propargylglycine?
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The CAS number for L-C-Propargylglycine is 23235-01-0, and its empirical formula is C5H7NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-C-Propargylglycine with an assay of ≥99.0% (TLC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety considerations when handling L-C-Propargylglycine?
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When handling L-C-Propargylglycine, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified under WGK Germany 3.
How is L-C-Propargylglycine shipped and exported?
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L-C-Propargylglycine is stored at 2-8°C and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a quote or sample for L-C-Propargylglycine?
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To request a quote or a sample of L-C-Propargylglycine, please contact our sales team through the Tech Serve Solutions website.
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