L-733,060 hydrochloride
L-733,060 hydrochloride (CAS: 148687-76-7), a potent neurokinin NK1 receptor antagonist, presents as a white solid. With a molecular weight of 439.82 g/mol and empirical formula C20H19F6NO · HCl, this compound is invaluable in scientific research. It serves as a critical tool for investigating the role of tachykinins and their receptors in various physiological and pathological processes, particularly within neuroscience and cell signalling studies.
- IUPAC
- (2S,3S)-3-[(3,5-bis(Trifluoromethyl)phenyl)methoxy]-2-phenylpiperidine hydrochloride
- Synonyms
- C20H19F6NO · HCl
Neuroscience Research
L-733,060 hydrochloride is employed to study the function of neurokinin NK1 receptors in the central nervous system. Its antagonist activity helps elucidate the pathways involved in pain perception, mood regulation, and other neurological functions.
Cell Signaling Studies
This compound is used to investigate the intracellular signalling cascades triggered by tachykinin receptor activation. Researchers utilize it to understand signal transduction mechanisms relevant to various cell types.
Pharmacological Tool
As a selective NK1 receptor antagonist, L-733,060 hydrochloride serves as a standard pharmacological tool for validating drug targets and developing novel therapeutics in conditions modulated by the tachykinin system.
| Molecular weight | 439.82 |
|---|---|
| Empirical formula | C20H19F6NO · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... TACR1(6869) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-733,060 hydrochloride used for?
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L-733,060 hydrochloride is used in scientific research as a neurokinin NK1 receptor antagonist, primarily for studies in neuroscience and cell signalling, investigating tachykinin pathways.
What is the CAS number and formula for L-733,060 hydrochloride?
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The CAS number is 148687-76-7, and its empirical formula is C20H19F6NO · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-733,060 hydrochloride with an assay of ≥98% (HPLC). It is supplied for research purposes and is not represented as USP, BP, or EP grade.
How should L-733,060 hydrochloride be handled and stored?
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Handle L-733,060 hydrochloride with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter. Store at 2-8°C. It is classified with WGK Germany 3.
Is L-733,060 hydrochloride a controlled substance?
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The provided data does not indicate that L-733,060 hydrochloride is a controlled substance.
How is L-733,060 hydrochloride shipped?
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L-733,060 hydrochloride is shipped according to industry best practices for temperature-sensitive research chemicals, typically under refrigerated conditions.
How can I request a sample or quote for L-733,060 hydrochloride?
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To request a sample or quote, please contact our sales team through the provided channels on the Tech Serve Solutions website.
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