L-750,667 trihydrochloride
L-750,667 trihydrochloride (CAS: 1021868-80-3), with a molecular weight of 527.66 g/mol, is a chemical compound identified by its empirical formula C18H19IN4 · 3HCl. It serves as a valuable antagonist, primarily utilised in research for characterising the extracellular domain of the D4 dopamine receptor. Its applications extend to cell biology and neuroscience research, contributing to the understanding of neurotransmission.
- IUPAC
- 3-[4-(4-Iodophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride
- Synonyms
- C18H19IN4 · 3HCl3-[4-(4-Iodophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride

Dopamine Receptor Research
L-750,667 trihydrochloride is instrumental in studies investigating the extracellular domain of the D4 dopamine receptor. It acts as an antagonist, aiding researchers in probing receptor function and signalling pathways.
Neuroscience and Cell Biology
This compound is applicable in broader neuroscience and cell biology research, particularly concerning dopaminergic systems and neurotransmission. It aids in understanding cellular responses and molecular mechanisms.
Bioactive Small Molecule Studies
As a bioactive small molecule, L-750,667 trihydrochloride can be employed in screening and validation studies within drug discovery and chemical biology.
| Molecular weight | 527.66 |
|---|---|
| Empirical formula | C18H19IN4 · 3HCl |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble10 mg/mL |
| Application | Useful in characterizing the extracellular domain of the D4 dopamine receptor.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD4(1815) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-750,667 trihydrochloride used for?
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L-750,667 trihydrochloride is primarily used in research for characterising the extracellular domain of the D4 dopamine receptor and in studies related to neuroscience, cell biology, and neurotransmission.
What is the CAS number and formula for L-750,667 trihydrochloride?
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The CAS number for L-750,667 trihydrochloride is 1021868-80-3, and its empirical formula is C18H19IN4 · 3HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-750,667 trihydrochloride as a research-grade chemical. TSS does not represent this product as USP, BP, or EP grade.
How should L-750,667 trihydrochloride be handled safely?
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When handling L-750,667 trihydrochloride, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. Consult the safety data sheet for detailed information. It is classified with WGK Germany 3.
How is L-750,667 trihydrochloride packed, shipped, and exported?
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L-750,667 trihydrochloride is carefully packed to ensure its integrity during transit. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a quote or sample for L-750,667 trihydrochloride?
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To request a quote or a sample of L-750,667 trihydrochloride, please contact the Tech Serve Solutions sales department through our website or by phone.
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