L-701,324
L-701,324 (CAS: 142326-59-8; C21H14ClNO3) is a high-purity chemical compound with a molecular weight of 363.79 g/mol. Supplied as a solid, this substance is primarily utilised in cell biology research, particularly within cell signalling, neuroscience, and the study of ion channels and neurotransmitters. Its applications focus on understanding excitatory amino acid pathways and ionotropic glutamate receptor modulation, making it a valuable tool for neurochemical investigations.
- IUPAC
- 7-Chloro-4-hydroxy-3-(3-phenoxy)phenylquinolin-2[1H]-one
- Synonyms
- C21H14ClNO37-Chloro-4-hydroxy-3-(3-phenoxy)phenylquinolin-2[1H]-one

Neuroscience Research
L-701,324 is employed in neuroscience to investigate ionotropic glutamate receptor modulators and NMDA receptor antagonists. It aids in studying neurotransmission mechanisms and signalling pathways within the central nervous system.
Cell Biology Studies
This compound serves as a valuable reagent in cell biology, particularly for research involving cell signalling. It is used to explore the function of ligand-gated ion channels and their role in cellular processes.
Excitatory Amino Acid Pathways
Researchers utilise L-701,324 to probe the complexities of excitatory amino acid signalling. Its application helps in understanding the physiological and pathological roles of these critical neurotransmitters.
| Molecular weight | 363.79 |
|---|---|
| Empirical formula | C21H14ClNO3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | DMSO: soluble36.4 mg/mL |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GRIN1(2902)rat ... Grin1(24408), Grin2a(24409) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-701,324 used for?
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L-701,324 is used in scientific research, particularly in neuroscience and cell biology, for studying ionotropic glutamate receptors, ion channels, and neurotransmission mechanisms.
What is the CAS number and molecular formula for L-701,324?
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The CAS number for L-701,324 is 142326-59-8, and its molecular formula is C21H14ClNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-701,324 with a minimum purity of 98% (HPLC), as verified by our specifications. We do not represent this product as USP, BP, or EP grade.
How should L-701,324 be handled safely?
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L-701,324 is a Warning substance with H315, H319, and H335 hazard statements, indicating skin, eye, and respiratory irritation. Appropriate PPE, including a dust mask (N95), eyeshields, and gloves, should be worn during handling. Ensure good ventilation.
Is L-701,324 a controlled substance?
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The provided data does not indicate that L-701,324 is a controlled substance.
How is L-701,324 packed and shipped?
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L-701,324 is typically supplied as a solid. Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and compliance with international shipping regulations for chemicals.
How can I request a quote or sample for L-701,324?
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To request a quote or sample for L-701,324, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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