L-685,458
L-685,458 (CAS: 292632-98-5), with the molecular formula C39H52O6N4 and a molecular weight of 672.85 g/mol, is a highly purified white solid. This compound serves as a critical tool in biochemical research, particularly within cell biology and neuroscience. Its primary applications involve investigating cell signaling pathways and exploring potential therapeutic avenues, leveraging its role as an approved therapeutic/drug candidate and bioactive small molecule.
- IUPAC
- (5S)-(t-Butoxycarbonylamino)-6-phenyl-(4R)hydroxy-(2R)benzylhexanoyl)-L-leu-L-phe-amide
- Synonyms
- C39H52O6N4(5S)-(t-Butoxycarbonylamino)-6-phenyl-(4R)hydroxy-(2R)benzylhexanoyl)-L-leu-L-phe-amide

Neuroscience Research
L-685,458 is utilized in neuroscience research to investigate signaling pathways, particularly those involving gamma-secretase activity. It aids in understanding complex cellular mechanisms relevant to neurological conditions.
Cell Biology Studies
As a bioactive small molecule, L-685,458 is employed in cell biology to probe cellular processes. Its defined chemical structure and purity make it suitable for controlled experiments examining cell function and signaling.
Drug Discovery and Development
Identified as an approved therapeutic/drug candidate, L-685,458 is a valuable compound in drug discovery. Researchers use it to explore new therapeutic targets and to validate potential treatment strategies.
| Molecular weight | 672.85 |
|---|---|
| Empirical formula | C39H52O6N4 |
| Assay | >96% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-685,458 used for?
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L-685,458 is used in neuroscience and cell biology research, particularly for studying cell signaling pathways. It is also recognised as an approved therapeutic/drug candidate, making it valuable in drug discovery.
What are the CAS number and formula for L-685,458?
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The CAS number for L-685,458 is 292632-98-5, and its empirical formula is C39H52O6N4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-685,458 with a purity of >96% as determined by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling requirements for L-685,458?
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Handling L-685,458 requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3.
How is L-685,458 shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including L-685,458, adhering to all necessary shipping and export regulations.
How can I request a sample or quote for L-685,458?
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To request a sample or a quote for L-685,458, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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