4-Fluorophenethyl isocyanate
4-Fluorophenethyl isocyanate (CAS: 65535-53-7; Formula: C<sub>8</sub>H<sub>8</sub>FNO) is a valuable organic fluorinated building block with a molecular weight of 165.16 g/mol. This compound serves as a key intermediate in the synthesis of complex molecules. Its reactive isocyanate group allows for versatile chemical transformations, making it useful in the development of novel materials and pharmaceutical agents.
Organic Synthesis Intermediate
4-Fluorophenethyl isocyanate is employed as a building block in multi-step organic syntheses. It is particularly useful for introducing the 4-fluorophenethyl moiety into various molecular structures.
Pharmaceutical Research
This compound can be utilised in the research and development of new pharmaceutical candidates. Its fluorinated structure may impart desirable pharmacokinetic properties to drug molecules.
Materials Science
The isocyanate functionality enables polymerisation or incorporation into functional materials, potentially leading to novel polymers or surface modifications.
| Molecular weight | 165.16 |
|---|---|
| Linear formula | FC6H4CH2CH2NCO |
| Assay | 97% |
| Boiling point | 232-233 °C(lit.) |
| Density | 1.1342 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5011(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 2206 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorophenethyl isocyanate used for?
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4-Fluorophenethyl isocyanate is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical agents and novel materials.
What are the CAS number and formula for 4-Fluorophenethyl isocyanate?
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The CAS number is 65535-53-7 and the molecular formula is C8H8FNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorophenethyl isocyanate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Fluorophenethyl isocyanate be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and respiratory protection due to its irritant and sensitising properties (H315, H319, H334, H335). Work in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive guidance.
Is 4-Fluorophenethyl isocyanate hazardous?
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Yes, 4-Fluorophenethyl isocyanate is classified as dangerous. It carries hazard statements including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled), and H335 (May cause respiratory irritation). The signal word is Danger.
How is 4-Fluorophenethyl isocyanate packed, shipped, and exported?
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4-Fluorophenethyl isocyanate is packed and shipped in compliance with international regulations for hazardous materials. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a sample or quote for 4-Fluorophenethyl isocyanate?
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To request a sample or quote, please contact our sales team through the website or by phone, providing your specific requirements.
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