2-Amino-3-nitropyridine-5-boronic acid pinacol ester
2-Amino-3-nitropyridine-5-boronic acid pinacol ester (CAS: 1032758-80-7) is a versatile organoboron compound with the molecular formula C11H16BN3O4 and a molecular weight of 265.07 g/mol. This heteroaryl boronate ester serves as a valuable building block in organic synthesis, particularly for the construction of complex molecules through cross-coupling reactions. Its structure incorporates both amine and nitro functional groups, alongside the reactive boronic ester moiety, enabling diverse chemical transformations.
- IUPAC
- 3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine,6-Amino-5-nitropyridine-3-boronic acid pinacol ester
- Synonyms
- 3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine, 6-Amino-5-nitropyridine-3-boronic acid pinacol ester
Organic Synthesis Building Block
This compound is widely employed as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. The boronic acid pinacol ester functionality readily participates in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds.
Medicinal Chemistry Research
Its unique structural features make it useful in the discovery and development of new therapeutic agents. The pyridine core and attached functional groups can be modified to create novel drug candidates with specific biological activities.
Materials Science
The compound may find applications in the synthesis of advanced materials, such as organic semiconductors or functional polymers, where precise molecular architectures are required.
| Molecular weight | 265.07 |
|---|---|
| Empirical formula | C11H16BN3O4 |
| Assay | 97% |
| Melting point | 169-174 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-3-nitropyridine-5-boronic acid pinacol ester used for?
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2-Amino-3-nitropyridine-5-boronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for constructing complex molecules in medicinal chemistry and materials science via cross-coupling reactions.
What is the CAS number and formula for this compound?
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The CAS number is 1032758-80-7 and the empirical formula is C11H16BN3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. This product is not classified as USP, BP, EP, or pharmacopoeia grade.
How should this chemical be handled?
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This compound is classified as a warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, avoiding dust formation and inhalation. Ensure adequate ventilation.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team through the website or call us directly to request a sample or a quotation for 2-Amino-3-nitropyridine-5-boronic acid pinacol ester.
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