L-4-Hydroxy-proline benzyl ester hydrochloride
L-4-Hydroxy-proline benzyl ester hydrochloride (CAS: 62147-27-7) is a proline derivative with the molecular formula C12H15NO3 · HCl and a molecular weight of 257.71 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and the development of unnatural amino acid derivatives. Its specific structure makes it useful in research and development within chemical biology.
Peptide Synthesis
Utilised as a protected amino acid derivative in the construction of peptides. The benzyl ester serves as a protecting group for the carboxyl functionality, allowing for controlled coupling reactions in solid-phase or solution-phase peptide synthesis.
Chemical Biology Research
Incorporated into novel molecular structures for probing biological pathways or developing new therapeutic agents. Its unnatural amino acid characteristics can impart unique properties to biomolecules.
Organic Synthesis Intermediate
Serves as a versatile intermediate for the synthesis of more complex organic molecules. The presence of the proline ring and functional groups allows for diverse synthetic transformations.
Proline Derivative Chemistry
A key reagent for researchers studying modified proline structures and their impact on chemical and biological systems. Useful in the development of constrained peptides or peptidomimetics.
| Molecular weight | 257.71 |
|---|---|
| Empirical formula | C12H15NO3 · HCl |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D −37±2°, c = 1% in methanol |
| Melting point | 162-165 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-4-Hydroxy-proline benzyl ester hydrochloride used for?
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L-4-Hydroxy-proline benzyl ester hydrochloride is primarily used as a building block in chemical synthesis, particularly in peptide chemistry, for creating unnatural amino acid derivatives, and in chemical biology research.
What is the CAS number and chemical formula for L-4-Hydroxy-proline benzyl ester hydrochloride?
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The CAS number is 62147-27-7 and the chemical formula is C12H15NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-4-Hydroxy-proline benzyl ester hydrochloride with an assay of ≥98.0% (HPLC). This is a research grade material and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should L-4-Hydroxy-proline benzyl ester hydrochloride be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. Ensure adequate ventilation and avoid dust formation.
Is L-4-Hydroxy-proline benzyl ester hydrochloride shipped internationally?
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Yes, Tech Serve Solutions exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally.
How can I request a quotation or sample?
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Please contact our sales team via the website or direct inquiry to request a quotation or sample for L-4-Hydroxy-proline benzyl ester hydrochloride.
What is the melting point of this compound?
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The melting point of L-4-Hydroxy-proline benzyl ester hydrochloride is reported to be 162-165 °C.
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